Bioinformatics tools have gained popularity in biology but little is known about their validity. We aimed to assess the early contribution of 415 single nucleotide polymorphisms (SNPs) associated with eight cardio-metabolic traits at the genome-wide significance level in adults in the Family Atherosclerosis Monitoring In earLY Life (FAMILY) birth cohort. We used the popular web-based tool SNAP ...

1 Chief of Transplant Services, Department of Surgery. Fundación Cardio-Infantil Bogotá, Colombia. 2 Gastroenterology and Hepatology Services, Department of Internal Medicine. Fundación CardioInfantil. Bogotá, Colombia 3 Chief of Gastroenterology Service, Department of Internal Medicine. Fundación Cardio-Infantil. Bogotá, Colombia 4 Chief of Hepatology Service. Department of Internal Medicine. ...

INTRODUCTION Cardiac biomarkers may be invaluable in establishing the diagnosis of acute myocardial infarction (AMI) in the ED setting. OBJECTIVE To assess the diagnostic indices of the Cardio Detect assay and the quantitative cardiac troponin T test, in diagnosing AMI in the ED, according to the time of onset of chest pain. METHODOLOGY A total of 80 eligible patients presenting with ischem...

OBJECTIVES: Measurements of the joint angles of the shoulder complex are important for diagnosis, assessment and monitoring of the treatment progression of movement disorders, provided that they can be seen as valid and reliable. The object of this study was to determine interand intra-rater reliability of manual goniometry and computerized biophotogrammetry for the assessment of range of motio...

BACKGROUND Patients with atherosclerotic cardio-cerebrovascular disease are at high risk of kidney dysfunction because of the overlap of several risk factors. The purpose of this study is to examine the prevalence and characteristics and risk factors for kidney dysfunction in the cardio-cerebrovascular disease population. METHODS Renal functions of 1012 patients with the cardio-cerebrovascula...