This prospective population-based study investigated whether having any internalizing mental disorder (INT) was associated with the presence and onset of cardiometabolic (CM) at 3-year follow-up; vice versa. Furthermore, we examined observed associations differed when using longer time intervals respectively 6 9 years. Data were used from four waves (baseline 3-, 6- 9-year follow-up) Netherland...

OBJECTIVE Mental health service users experience high rates of cardiometabolic disorders and have a 20-25% shorter life expectancy than the general population from such disorders. Clinician-led health behavior programs have shown moderate improvements, for mental health service users, in managing aspects of cardiometabolic disorders. This study sought to potentially enhance health initiatives b...

Nobiletin (NOB) chemically known as 5, 6, 7, 8, 3, 4-hexamethoxyflavone is a polymethoxylated flavonoid that predominantly found in the peel of citrus fruits. Animal studies and limited number clinical trials suggest NOB has multifunctional biological activities such protection against obesity related cardiometabolic disorders, neuroprotection, antidiabetic, anticancer, anti-allergy, antioxidan...

1 Centre for Comparative Genomics, Murdoch University, Murdoch, WA, Australia, 2 Health Informatics Society of Australia, North Melbourne, VIC, Australia, 3 School of Medicine, University of Western Australia, Perth, WA, Australia, 4 Lipid Disorders Clinic, Cardiometabolic Service, Royal Perth Hospital, Perth, WA, Australia, 5 Centre for Neuromuscular and Neurological Disorders, University of W...

OBJECTIVES A growing body of evidence emerges that obesity, metabolic syndrome, type 2 diabetes and cardiovascular disease are intimately related to chronic inflammation. METHODS A narrative review summarizing the most recent data of the literature describing the pathological implications of inflammation in obese patients with cardiometabolic disorders. RESULTS Besides high-sensitive C-reac...

Background and Aims: The adipokine fatty-acid binding protein 4 (FABP4) has been implicated in the pathogenesis of cardiometabolic disorders. Blocking action FABP4 through genetic or pharmacological means a preclinical setting analyzing effects genetically reduced expression humans is suggested to protect against obesity-related metabolic derangements atherosclerosis. As cardiovascular disease ...

Psoriasis is a chronic, systemic inflammatory disease associated with several cardiometabolic comorbidities, such as obesity, insulin resistance, dyslipidemia, and hypertension, and with clinically significant increased risk of cardiovascular disease and cardiovascular mortality. These comorbidities are components of the metabolic syndrome. Multiple epidemiologic studies have revealed a high pr...

Cardiometabolic disorders are among the leading causes of mortality in human population. Dietary polyphenols exert beneficial effects on cardiometabolic health humans. Molecular mechanisms, however, not completely understood. Aiming to conduct in-depth integrative bioinformatic analyses elucidate molecular mechanisms underlying protective health, we first conducted a systematic literature searc...

Syzygium cumini (Myrtaceae) is a worldwide medicinal plant traditionally used in herbal medicines due to its vaunted properties against cardiometabolic disorders, which include: antihyperglycemic, hypolipemiant, antiinflammatory, cardioprotective, and antioxidant activities. These properties have been attributed to the presence of bioactive compounds such as phenols, flavonoids, and tannins in ...