نتایج جستجو برای: cationic amino acid transporter 2

تعداد نتایج: 3164682  

Journal: :The Biochemical journal 1999
D K Kakuda M J Sweet C L Mac Leod D A Hume D Markovich

Activated macrophages require l-arginine uptake to sustain NO synthesis. Several transport systems could mediate this l-arginine influx. Using competition analysis and gene-expression studies, amino acid transport system y+ was identified as the major carrier responsible for this activity. To identify which of the four known y+ transport-system genes is involved in macrophage-induced l-arginine...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه اراک - دانشکده علوم پایه 1390

در این پایان نامه، ابتدا به شرح روش تهیه و بررسی خواص طیفی و مغناطیسی چهار کمپلکس کروم(iii) و دو کمپلکس منگنز(ii) با فرمول های بسته cr(l)3 ، cr2(l)2(oh)5(ch3coo) ، mn(l)4cl2 و mn(l)4(no3)2 پرداخته شده است که در آن هاl= 2-carboxylic acid pyridine ، 2-amino-4-methyle pyridine، 2-amino-3-methyle pyridine ،3-methanol pyridine و acid hydrazide 4-pyridine carboxylic می باشد. در ادامه، دو لیگاند با...

Journal: :The Biochemical journal 2002
Sabine Wolf Annette Janzen Nicole Vékony Ursula Martiné Dennis Strand Ellen I Closs

Member 4 of human solute carrier family 7 (SLC7A4) exhibits significant sequence homology with the SLC7 subfamily of human cationic amino acid transporters (hCATs) [Sperandeo, Borsani, Incerti, Zollo, Rossi, Zuffardi, Castaldo, Taglialatela, Andria and Sebastio (1998) Genomics 49, 230-236]. It is therefore often referred to as hCAT-4 even though no convincing transport activity has been shown f...

Journal: :Free Radical Biology and Medicine 2021

During vascular inflammation, the leukocyte-derived enzyme myeloperoxidase (MPO) is transcytosed across endothelium and into sub-endothelial extracellular matrix, where it promotes endothelial dysfunction by catalytically consuming nitric oxide (NO) produced NO synthase (eNOS). In presence of chloride ions hydrogen peroxide (H2O2), MPO forms oxidant hypochlorous acid (HOCl). Here we examined sh...

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