1Department of Paediatrics, Khoo Teck Puat-University Children’s Medical Institute, National University Hospital, Singapore Address for Correspondence: Dr Loke Kah Yin, Department of Paediatrics, Khoo Teck Puat-University Children’s Medical Institute, National University Hospital, 5 Lower Kent Ridge road, Singapore 119074. Email: [email protected] Early Infl uences in Childhood Obesity—K...

Immunoglobulin A (IgA) provides protection against pathogens at mucosal surfaces. Chemotactic responses have been hypothesized to target IgA plasma cells involved in mucosal immune responses. We show here that thymus-expressed chemokine (TECK, CCL25) is a potent and selective chemoattractant for IgA antibody-secreting cells (ASC), efficiently recruiting IgA-producing cells from spleen, Peyer's ...

Chemokines are likely to play an important role in regulating the trafficking of developing T cells within the thymus. By using anti-CD3varepsilon treatment of recombinase-activating gene 2 (Rag2-/-) mice to mimic pre-TCR signaling and drive thymocyte development to the double positive stage, we have identified murine GPR-9-6 as a chemokine receptor whose expression is strongly induced followin...

We determine the effects of a delayed or immediate tax cut with or without a “sunset” feature in a real customer-market, nonRicardian economy. Our model incorporates both the supply-sider channel as well as the Feldstein-Rubin-Summers channel. We show that a tax cut may depress both the real asset price and employment. The presence of the paradoxical result of employment contraction does not wo...

In open-economy macroeconomics there is a monetary model in the Keynesian tradition that is deemed serviceable for analyzing the short run and there is a nonmonetary neoclassical theory thought capable of handling the long run. But do the Keynesian and neoclassical models meet the challenges thrown out by the main events of the past few decades—the ’80s shock to Europe taking the form of an ext...