The association of celiac disease and type I diabetes mellitus has been known for some time. This study was undertaken to investigate the prevalence of celiac disease (CD) in diabetic children and adolescents. Eighty-seven patients (44 females, 43 males) aged 218 years, with type I diabetes participated in this study. A group of 87 healthy unrelated girls and boys matched for age and gender ser...

The study of lymphatic vessels and lymphatic tumors has been hampered with difficulty due to the overlapping morphological features between blood and lymphatic endothelial cells, as well as to the lack of specific lymphatic endothelial markers. Over the last few years, lymphatic vessels and lymphangiogenesis have received great attention owing to their putative implications in terms of metastat...

Objective(s) The aim of this study was to evaluate the expressions of two angiogenic immune-markers (CD-31 and VEGF), and one proliferative immune-marker (Ki-67) in oral pyogenic granulomas (PG), hemangiomas (Hem) and inflammatory gingivitis (IG). Materials and Methods Sixty cases of PG, Hem and IG (twenty cases each) were examined. Immunohistochemical (IHC) staining was performed based on r...

objective(s) the aim of this study was to evaluate the expressions of two angiogenic immune-markers (cd-31 and vegf), and one proliferative immune-marker (ki-67) in oral pyogenic granulomas (pg), hemangiomas (hem) and inflammatory gingivitis (ig). materials and methods sixty cases of pg, hem and ig (twenty cases each) were examined. immunohistochemical (ihc) staining was performed based on rout...

BACKGROUND Cadmium (Cd) is a human toxicant and carcinogen. Genetic variation might affect long-term accumulation. Cd is absorbed via iron transporters. OBJECTIVES We evaluated the impact of iron homeostasis genes [divalent metal transporter 1 (SLC11A2), transferrin (TF), transferrin receptors (TFR2 and TFRC), and ferroportin (SLC40A1)] on Cd accumulation. METHODS Subjects were nonsmoking w...

We read with interest the paper of Komorowski et al. reporting the discovery of two autoantigenic targets, CUB and zona pellucida-like domain-containing protein 1 (CUZD1) and glycoprotein 2 (GP2), in Crohn's disease (CD).1 The identification of GP2 as CD-specific target and the role of antibodies to GP2 (anti-GP2) in the serology and pathophysiology of CD have been reported extensively.2,3 Unfo...

AIM This study evaluated serum levels of zinc in patient with CD compare to healthy subjects. BACKGROUND Celiac disease (CD) is characterized by small intestinal malabsorption of nutrients as a consequence of ingestion of wheat gluten. Zinc is an essential trace element that it has vital biological functions. PATIENTS AND METHODS Sera of 30 celiac cases and 30 healthy normal cohorts as cont...

Cushing's disease (CD) remains a medical challenge, with many questions still unanswered. Successful treatment of CD patients is closely related to correct approach to syndromic and etiological diagnosis, besides the experience and talent of the neurosurgeon. Pituitary transsphenoidal adenomectomy is the treatment of choice for DC. Assessment of remission after surgery and recurrence in the lon...

The aim of the present study was to evaluate the diagnostic value of five serological antibodies, perinuclear antineutrophil cytoplasmic antibody (pANCA), anti-Saccharomyces cerevisiae antibodies [ASCA; ASCA-immunoglobulin (IgG)and ASCA-IgA], Escherichia coli outer membrane porin C antibody (anti-OmpC) and CBir1 flagellin antibody for detection in inflammatory bowel diseases. Whether the antibo...

OBJECTIVE Dipeptidyl peptidase IV (DPP IV/CD26) is involved in the degradation of proline-rich proteins such as gliadin and in modulation of the immune response. The aim of this study was to examine the possible causal connection between DPP IV enzyme activities and celiac disease (CD) in children. PATIENTS AND METHODS Intestinal mucosal biopsy specimens were obtained from 97 patients. The pa...