نتایج جستجو برای: cd203c
تعداد نتایج: 112 فیلتر نتایج به سال:
Basophils are rare immune cells, accounting for 0-2% of peripheral blood leukocytes, and known to be involved in defense against parasitic infections allergic diseases. Recent studies have revealed their pathogenic role autoimmune diseases such as systemic lupus erythematosus via type 2 cytokine production supporting plasma cells. Bullous pemphigoid (BP) is an blistering disease caused by IgG a...
Background: Allergy to peach gibberellin-regulated protein(GRP), Pru p 7, is severe and possibly enhanced by co-factors. In addition, recent studies suggested that 7 allergy could be due cross-reactivity with other GRPs, such as Japanese apricot GRP (Pru m 7), orange (Cit s 7) cedar pollen (Cry j 7). However, the natural history of remains unclear. this study, we investigated course basophil ac...
A 54-year-old woman was diagnosed with infiltrative ductal breast carcinoma. Two years after treatment, the patient developed an acute myeloid leukemia (AML) which harbored del(11q23) in 8% of the blast cells. The patient was submitted for allogeneic stem cell transplantation (aSCT) from her HLA-compatible sister. Ten months after transplantation, she relapsed with an AML with basophilic matura...
relationship to proportion of regulatory T cells. Methods: Forty-five patients with history of systemic symptoms of allergy to Hymenoptera venom were included. Basophil reactivity before the treatment and after one year of allergen immunotherapy (AIT) was measured by CD63 expression, CD203c marker used for basophil identification. Cells were stimulated by aqueous solution of allergen in concent...
The diagnosis of immediate allergy is mainly based upon an evocative clinical history, positive skin tests (gold standard) and, if available, detection of specific IgE. In some complicated cases, functional in vitro tests are necessary. The general concept of those tests is to mimic in vitro the contact between allergens and circulating basophils. The first approach to basophil functional respo...
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