نتایج جستجو برای: cd68 antigen

تعداد نتایج: 202582  

Journal: :Iraqi journal of Veterinary Sciences 2023

Evaluation of the wound age and vitality is a persistent problem for forensic examinations to determine when injuries occurred whether during antemortem or post-mortem period. This study aimed use inflammatory cells mediators as target marker in samples rats. Wound skin (n=39) were collected from groups aged 30, 60, 180, 360 min within same periods with control (unwounded group). Immunohistoche...

2012
Noemí Eiró Iván Pidal Belen Fernandez-Garcia Sara Junquera Maria L. Lamelas José M. del Casar Luis O. González Alfonso López-Muñiz Francisco J. Vizoso

Tumors are infiltrated by macrophages, T and B-lymphocytes, which may favor tumor development by promoting angiogenesis, growth and invasion. The aim of this study was to investigate the clinical relevance of the relative amount of macrophages (CD68⁺), T-cells (CD3⁺ and B-cells (CD20⁺) at the invasive front of breast carcinomas, and the expression of matrix metalloproteases (MMPs) and their inh...

Journal: :Mediators of Inflammation 2002
Shinya Sakai Naoki Mantani Toshiaki Kogure Hiroshi Ochiai Yutaka Shimada Katsutoshi Terasawa

BACKGROUND Influenza virus is a worldwide health problem with significant economic consequences. To study the gene expression pattern induced by influenza virus infection, it is useful to reveal the pathogenesis of influenza virus infection; but this has not been well examined, especially in vivo study. AIMS To assess the influence of influenza virus infection on gene expression in mice, mRNA...

2016
Johanna Mucke Annika Hoyer Ralph Brinks Ellen Bleck Thomas Pauly Matthias Schneider Stefan Vordenbäumen

BACKGROUND Inhomogeneity of immune cell distribution in the synovial sublining layer was analyzed in order to improve our mechanistic understanding of synovial inflammation and explore potential refinements for histological biomarkers in rheumatoid arthritis (RA) and osteoarthritis (OA). METHODS Synovial tissue of 20 patients (11 RA, 9 OA) was immunohistochemically stained for macrophages (CD...

Journal: :Circulation research 2011
Giulia Chinetti-Gbaguidi Morgane Baron Mohamed Amine Bouhlel Jonathan Vanhoutte Corinne Copin Yasmine Sebti Bruno Derudas Thérèse Mayi Gael Bories Anne Tailleux Stephane Haulon Christophe Zawadzki Brigitte Jude Bart Staels

RATIONALE A crucial step in atherogenesis is the infiltration of the subendothelial space of large arteries by monocytes where they differentiate into macrophages and transform into lipid-loaded foam cells. Macrophages are heterogeneous cells that adapt their response to environmental cytokines. Th1 cytokines promote monocyte differentiation into M1 macrophages, whereas Th2 cytokines trigger an...

2017
Chun-Xia Ren Rui-Xue Leng Yin-Guang Fan Hai-Feng Pan Bao-Zhu Li Chang-Hao Wu Qiang Wu Na-Na Wang Qi-Ru Xiong Xiao-Ping Geng Dong-Qing Ye

The aims of the present study were to determine whether the changes in density and location of CD68-positive and CD206-positive macrophages contribute to progression of hepatocellular carcinoma (HCC) and to evaluate prognostic values of these cells in post-surgical patients. A retrospective study involving 268 HCC patients was conducted. CD68-positive and CD206-positive macrophage infiltration ...

Journal: :Anticancer research 2009
Tadej Strojnik Rajko Kavalar Irena Zajc Eleftherios P Diamandis Katerina Oikonomopoulou Tamara T Lah

AIMS To evaluate the expression of CD68 and kallikrein 6 in human gliomas, and investigate their prognostic significance for survival of brain cancer patients in comparison to some known prognostic markers. PATIENTS AND METHODS Histological sections of 51 primary astrocytic tumours (11 benign, 40 malignant) were immunohistochemically stained for CD68, cathepsin B, kallikrein 6 and Ki-67. CD68...

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