Received ; accepted – 2 – ABSTRACT We study the cluster mass function in mixed dark matter (MDM) models, using two COBE normalized simulations with Ω h = 0.26 and n = 1.2, and Ω h = 0.14 and n = 1.05, both with 2 massive ν's (MDM1 and MDM2, respectively). For the sake of comparison, we also simulate a CDM model with spectral index n = 0.8 (TCDM), also COBE normalized. We argue that, in our non–...

The manufacture of human mesenchymal stem cells (hMSCs) for clinical applications requires an appropriate growth surface and an optimized, preferably chemically defined medium (CDM) for expansion. We investigated a new protein/peptide-free CDM that supports the adhesion, growth, and detachment of an immortalized hMSC line (hMSC-TERT) as well as primary cells derived from bone marrow (bm-hMSCs) ...

Among the benefits of agent-based modeling is parallel development and implementation of components. Integrating large numbers of agents developed by many is, however, a significant challenge. Further, architectural changes can require significant redesign. We have developed CDM-S, the Constructionist Design Methodology for Simulation, an agent-oriented methodology for developing, implementing ...

The paper presents a Construction Database Model (CDM) used for the conceptual level modelling of design objects. A primary intention of the CDM model is modelling hierarchically structured objects and construction dependencies among objects. CDM is an attribute based data model. The CDM model represents various abstractions identiied in the semantic database models GSM, IFO, SAM* and FDM by me...

We discuss several aspects of astroparticle physics pertaining to a new model with MeV cold dark matter particles, which annihilate to electron-positron pairs in a manner yielding the correct CDM density required today, and explaining the enhanced electron-positron annihilation line from the center of the Galaxy. We note that the mass of the vector meson mediating the annihilations, should exce...

This paper discusses the role of the Clean Development Mechanism (CDM) on the market for carbon quotas and countries’ commitments to reduce their carbon emission levels. We show that the CDM contributes to an efficient funding of clean technology investments in least developed countries. However, the CDM is not neutral on the global level of carbon emissions as it entices countries to raise the...

Discounting the value of emission credits has been proposed as a possible approach for addressing some of the shortcomings of the Clean Development Mechanism (CDM). It could be used to compensate for non-additional CDM projects; to increase the incentive for advanced developing countries to move from the CDM to own mitigation commitments; and to improve the competitiveness of less developed cou...

Myotonic dystrophy type 1 is the commonest neuromuscular disease affecting adults. It is inherited in an autosomal dominant manner, and is linked to a dynamic expansion of a CTG triplet repeat localised to chromosome 19q13.3. The phenotype can be divided into four main groups: mild, juvenile, classical, and congenital. The most severe form of the condition is observed in congenitally affected i...

OBJECTIVES A distributed research network (DRN) has the advantages of improved statistical power, and it can reveal more significant relationships by increasing sample size. However, differences in data structure constitute a major barrier to integrating data among DRN partners. We describe our experience converting Electronic Health Records (EHR) to the Observational Health Data Sciences and I...

Solar home systems are an excellent fit for the Clean Development Mechanism under the Kyoto Protocol because they directly displace greenhouse gas emissions while contributing to sustainable rural development. Selling emission reduction credits under the CDM could provide additional revenues for SHSs. However, high transaction costs related to CDM procedures might prevent SHSs from benefiting f...