نتایج جستجو برای: cell genomics

تعداد نتایج: 1708627  

Journal: :Journal of Dental Research 2020

2017
Enrico Tiacci Valentina Pettirossi Gianluca Schiavoni Brunangelo Falini

Hairy cell leukemia (HCL) is a chronic mature B-cell neoplasm with unique clinicopathologic features and an initial exquisite sensitivity to chemotherapy with purine analogs; however, the disease relapses, often repeatedly. The enigmatic pathogenesis of HCL was recently clarified by the discovery of its underlying genetic cause, the BRAF-V600E kinase-activating mutation, which is somatically an...

2017
Yizhi Song Anne‐Kristin Kaster John Vollmers Yanqing Song Paul A. Davison Martinique Frentrup Gail M. Preston Ian P. Thompson J. Colin Murrell Huabing Yin C. Neil Hunter Wei E. Huang

Cell sorting coupled with single-cell genomics is a powerful tool to circumvent cultivation of microorganisms and reveal microbial 'dark matter'. Single-cell Raman spectra (SCRSs) are label-free biochemical 'fingerprints' of individual cells, which can link the sorted cells to their phenotypic information and ecological functions. We employed a novel Raman-activated cell ejection (RACE) approac...

Journal: :The Journal of Cell Biology 2000
Ira Mellman

ens , in a sense the frontier has been officially closed on four of the most widely used and extensively studied species on earth. It is obvious that the closing of this frontier will open many new ones, creating directions and experimental opportunities for biologists and biomedical scientists for decades to come. However, the actual nature of these directions and opportunities remains uncerta...

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