background: the hla class i molecules serve as ligands for both t cell receptors and killer cell immunoglobulin-like receptors (kirs). objective: we investigated the hlac and hla-bw4 alleles as well as kirs expression on cd56 positive lymphocytes to evaluate whether these genes and molecules could influence ankylosing spondylitis (as) susceptibility, alone or in combination. methods: we typed 4...

A part of the immune system that improves (complements) the ability of antibodies and phagocytic cells to clear microorganisms and injured cells from an organism, attacks the pathogen's cell membrane, and encourages inflammation called complement system. It is main part of immune system. Over thirty proteins and protein pieces compose the complement system, including cell membrane receptors, an...

introduction: g-proteins have an important role in the cell signaling of numerous receptors. the situation of g-proteins in health and disease and their critical role in the development of diabetic side effects is an interested scientific field. here, the changes in the expression of g-protein subunits (gαi, gαs and gβ) were evaluated in hyperglycemic situation of pc12 cells as a cellular model...

background: learning and memory are the most intensively studied subjects in neuroscience. two sites of mammalian brain which are important in learning and memory are ca1 region of hippocampus and purkinje cell layer of cerebellum. so, the aim of present investigation was to study of the effect of ovariectomy and passive avoidance learning on nr1 subunit of n-methyl-d-aspartate (nmda) receptor ...

Abstract NK cells mediate anti-leukemic immunosurveillance in AML. We hypothesized that impaired predict poor outcomes analyzed the expression of receptors on CD56 cell subsets and their corresponding ligands CD45dim blast by flow cytometry 100 AML 17 healthy bone marrows. Risk stratification, complete remission, relapse, measurable residual disease, overall survival, relapse-free ligand expres...