نتایج جستجو برای: cell restoring

تعداد نتایج: 1696473  

Journal: :Studies in History and Philosophy of Science Part B: Studies in History and Philosophy of Modern Physics 2015

Journal: :British Dental Journal 2018

Journal: :Genes & development 2015
Renáta Váraljai Abul B M M K Islam Michael L Beshiri Jalees Rehman Nuria Lopez-Bigas Elizaveta V Benevolenskaya

The retinoblastoma tumor suppressor protein pRb restricts cell growth through inhibition of cell cycle progression. Increasing evidence suggests that pRb also promotes differentiation, but the mechanisms are poorly understood, and the key question remains as to how differentiation in tumor cells can be enhanced in order to diminish their aggressive potential. Previously, we identified the histo...

2016
Xiumin Wang Yingying Wang Gang Xiao Jinglong Wang Lidong Zu Mingang Hao Xueqing Sun Yujie Fu Guohong Hu Jianhua Wang

Non-small cell lung cancer (NSCLC), which accounts for more than 80% of lung cancers, is a leading cause of cancer mortality worldwide. However, the mechanism underlying its progression remains unclear. Here we found that HIC1 promoter was heavily methylated in NSCLC cell lines and tissues contributing to its low expression compared to normal controls. Restoring HIC1 expression inhibited migrat...

Behnamoddin Jameie, Parvin Pourmasoumi,

By Using the modeling of the mesenchymal (bone marrow) stem cell nanoparticles, the reinstatement of the immune system leads to the treatment of MS, result in the formation of a new immune system for the body by stem cell. The presence of stem cells promotes and strengthens myelination, and that, using simulation and 3D modeling, stem cells can be transmitted correctly to the target and place o...

Journal: :Cold Spring Harbor perspectives in medicine 2014
Erin R Burnight Luke A Wiley Robert F Mullins Edwin M Stone Budd A Tucker

Viral-mediated gene augmentation therapy has recently shown success in restoring vision to patients with retinal degenerative disorders. Key to this success was the availability of animal models that accurately presented the human phenotype to test preclinical efficacy and safety. These exciting studies support the use of gene therapy in the treatment of devastating retinal degenerative disease...

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