We sought to investigate the effect of nerve growth factor (NGF) expression on the formation and prognosis of cerebral aneurysms. Forty-eight cases were selected following a diagnosis of cerebral aneurysm using computed tomography angiography and surgical confirmation. Thirty-four cases of healthy deaths were also chosen. The tissue was tested for NGF expression changes by reverse-transcription...

A 30-year-old man presented with a history of several convulsive episodes. A CT scan showed a calcified focus in the right temporal lobe. Cerebral angiography yielded no abnormal findings. At craniotomy, the M3 portion of the middle cerebral artery was found to terminate with a blind end at the junction with the calcified mass. A pathological diagnosis of an ossified cerebral aneurysm was made....

Cerebral Vasospasm With Infarction • A case of intense unilateral cerebral vasospasm with appropriate neurological deficit following rupture of a posterior communicating aneurysm was followed with serial angiography. Associated with the initially intense spasm was subsequent regional hyperperfusion with early venous filling which disappeared as signs of focal cerebral atrophy ensued. These angi...

Now, more and more patients are suffering cerebral aneurysm. However, long training time limits the rapid growth of cerebrovascular neurosurgeons. Here we developed a novel cerebral aneurysm simulator which can be better represented the dynamic bulging process of cerebral aneurysm The proposed simulator features the integration of a hollow elastic vascular model, a skull model and a brain model...

Owing to the rapid development of intervention techniques and devices, endovascular coil embolization of cerebral arteries has become standardized. It is particularly preferred when a patient presents with an unruptured intracranial aneurysm of the posterior communicating artery (PcomA). However, the risk of thrombogenic complications of the coil migration may also result in a large cerebral in...

We previously found that aspirin decreases the risk of cerebral aneurysm rupture in humans. We aim to assess whether a sex differential exists in the response of human cerebral aneurysms to aspirin and confirm these observations in a mouse model of cerebral aneurysm. A nested case-control analysis from the International Study of Unruptured Intracranial Aneurysms was performed to assess whether ...

BACKGROUND Atrial septal aneurysm has been considered a potential source of cardiogenic embolism for many years. The present study evaluated the prevalence and characteristics of atrial septal aneurysm in a patient population with stroke and normal carotid arteries compared to a control population without stroke. METHODS A total of 606 patients were enrolled between November 1990 and December...

To date, S. alactolyticus endocarditis complicated by middle cerebral artery aneurysm has not been reported. We describe the case of a 65-year-old female with a history of hypertrophic cardiomyopathy with left ventricular outflow tract obstruction presenting with confusion and a apical holosystolic murmur. Angiography of the brain identified new bilobed left middle cerebral artery aneurysm. Ser...

A 48-year-old female presented with a unique combination of ruptured aneurysm of the right middle cerebral artery (MCA) manifesting as sudden loss of consciousness associated with arteriovenous malformation (AVM) in the right parietal lobe and left primitive trigeminal artery (PTA) variant. Angiography revealed the right MCA aneurysm, AVM fed by the right anterior cerebral artery and MCA, and c...

A 42-year-old man presented with right hemiparesis. Brain imaging showed acute infarction in the left middle cerebral artery territory and a thrombosed aneurysm (figure). Extracranial carotid artery was normal. EKG and echocardiography were normal. Holter monitoring for 24 hours revealed no cardiac source of embolism. Cerebral infarction is a rare complication of unruptured aneurysm.1 The imagi...