The combination effect of miconazole with polygodial against Candida albicans was investigated by an in vitro checkerboard method. Isobolograms, fractional inhibitory concentration (FIC), and fractional fungicidal concentration (FFC) indices were used for evaluating the interaction between compounds combined. The combination of miconazole with polygodial exhibited strong synergism on both fungi...

A number of inhibitors of the essential Mycobacterium tuberculosis mycolic acid transporter, MmpL3, are currently under development as potential novel antituberculosis agents. Using the checkerboard method to study the interaction profiles of various antituberculosis drugs or experimental compounds with two different chemotypes inhibiting this transporter (indolcarboxamides and adamantyl ureas)...

It is believed that human primary visual cortex (V1) increases activity with increasing temporal frequency of a visual stimulus. Two kinds of visual stimulus were used in the previous studies, one is patterned-flash stimulus with a fixed onset period and an increasing average luminance with the increase of temporal frequency, the other is contrast reversing flickering checkerboard or grating wi...

The area of topology optimization of continuum structures of which is allowed to change in order to improve the performance is now dominated by methods that employ the material distribution concept. The typical methods of the topology optimization based on the structural optimization of two phase composites are the so-called variable density ones, like the SIMP (Solid Isotropic Material with Pe...

This supplementary document includes the following sections. Section 1 describes another multiplexed illumination method using a multiplexing scheme similar to that in Lemma 4.1 in the paper. The method also extracts N direct illuminations from 2N + 1 images. Section 2 shows detailed derivation of the SNR analysis results. Section 3 discusses about the pros and cons of direct/global separation ...

CHECKERBOARD codes are two-dimensional binary codes that are designed to satisfy specific constraints [1], [2]. An example is the two-dimensional rectangular binary arrays that satisfy the (d, k) run-length constraint— there are at most k 0’s and the number of 0’s between any neighboring 1’s is at least d in each row and column [3]–[7]. It may naturally arise from data storage on a surface [8],...

A bifield stimulation method for rapidly obtaining retinotopic maps in human occipital cortex using functional MRI was compared to conventional unifield stimulation. While maintaining central fixation, each participant viewed the conventional display, consisting of a single rotating checkerboard wedge and, in a separate run, the bifield display, consisting of two symmetrically placed rotating c...

As in the case of two-dimensional topology design optimization, numerical instability problems similar to the formation of two-dimensional checkerboard patterns occur if the standard eight-node conforming brick element is used. Motivated by the recent success of the two-dimensional non-conforming elements in completely eliminating checkerboard patterns, we aim at investigating the performance o...

In order to measure the large density-gradient fields of fluids such as underwater shock waves, we employed a fast Fourier demodulation called Fast Checkerboard Demodulation (FCD) method in Background Oriented Schlieren (BOS) technique. BOS is simple image-based measurement technique that detects apparent displacement (local distortion) background image caused by density gradient fluid front ba...

Filtering has been a major approach used in the homogenization-based methods for structural topology optimization to suppress the checkerboard pattern and relieve the numerical instabilities. In this paper a bilateral filtering technique originally developed in image processing is presented as an efficient approach to regularizing the topology optimization problem. A nonlinear bilateral filteri...