Based on sequence homologies among the human, porcine, rat, and mouse genes for the LH receptor (LHR), overlapping partial fragments of LHR complementary DNAs (cDNAs) were multiplied from marmoset monkey testicular RNA using reverse transcription-PCR. Ligations of the individual cDNA fragments generated a full-length monkey LHR cDNA (2031 bp) containing the complete amino acid-coding sequence (...

The angiographic anatomy of the external carotid artery system in the rhesus monkey is described. Similarities and differences between human and monkey anatomy are emphasized, as well as anatomic variations and potential collateral pathways. Superselective angiography and embolization in the external carotid artery system of the rhesus monkey proved to be technically feasible and potentially re...

Japanese monkey liver contains multiple forms of dihydrodiol dehydrogenase with 3(20)alpha-hydroxysteroid dehydrogenase activity. Here we have purified the major and minor forms (DD1 and DD4) of the enzyme from Cynomolgus monkey liver, and isolated cDNA species for the two enzyme forms by reverse transcription-PCR. The cDNAs encoded proteins comprising of 323 amino acids, in which the sequence ...

1. Visual responses were recorded from neurones in the magnocellular and parvocellular layers of the lateral geniculate nucleus (LGN) of the thalamus in two species of New World monkeys - the diurnal squirrel monkey (Saimiri sciureus) and the nocturnal owl monkey (Aotus trivirgatis). Recording sites were reconstructed in postmortem tissue and comparisons were made between the response propertie...

It is known that the squirrel monkey, marmoset, and other related New World (NW) monkeys possess three high-frequency alleles at the single X-linked photopigment locus, and that the spectral sensitivity peaks of these alleles are within those delimited by the human red and green pigment genes. The three alleles in the squirrel monkey and marmoset have been sequenced previously. In this study, t...

BACKGROUND Information is needed regarding analytical characteristics of cardiac troponin (cTn) assays used in preclinical studies. METHODS We measured cTnI and cTnT in serum from normal animals and animals with induced myocardial injury [Sprague-Dawley (SD) and Wistar rats, beagle dogs, and rhesus (Rh) and cynomolgus (Cy) monkeys]. We evaluated the following assays: for cTnI, Abbott Architec...

RESULTS. By RT-PCR, -CM mRNA was detected at a low level in mouse and monkey retina and in the RPE-choroid of the monkey but not of the mouse. Conversely, -CM mRNA was expressed at a low level in both human and bovine RPEchoroid, but not in the retina of either. RPE primary cultured cells of the monkey also showed -CM mRNA expression, although the three human lines did not. In addition, of nine...