BACKGROUND/AIMS Pravastatin, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, has been shown to inhibit growth and to induce apoptosis in human hepatocellular carcinoma (HCC) cells. However, the potential benefit of pravastatin in HCC patients has still not been characterized, which prompted us to test the efficacy of pravastatin in patients with advanced HCC. METHODS We investiga...

the imaging of hepatocellular carcinoma (hcc) is challenging and plays a crucial role in the diagnosis and staging of the disease. a variety of imaging modalities, such as ultrasound, computed tomography (ct), magnetic resonance imaging (mri) and nuclear medicine are currently used in evaluating patients with hcc. although the best option for the treatment of these cases is hepatic resection or...

Intrahepatic cholangiocarcinoma (ICC) is a rare disease with rising incidence. While surgical resection the only curative option, process often identified in advanced stages, as this malignancy remains clinically silent early development. Only one-third of patients are eligible for at time diagnosis. For who cannot undergo resection, intra-arterial therapies reasonable palliative treatment opti...

Background. Radiation therapy for locally advanced nasopharyngeal carcinoma (NC) has a high incidence of fatal complications, which leads to absolute contraindications External Beam Therapy (EBRT). Chemoembolization tumor significantly reduces these risks and allows EBRT. The aim this study was assess response rate after chemoembolization Objective. To evaluate the in patients with cancer treat...

Despite advances in current treatment options, Hepatocellular Carcinoma (HCC) recurrence still presents as a significant clinical challenge. After initial treatment, HCC occurs considerable portion of patients without an available standardized protocol for managing such incident. Recurrence advanced liver disease may make surgical options impossible, which case, locoregional therapy should be c...

At an intermediate or advanced stage, i.e. stage B or C, based on the Barcelona Clinic Liver Cancer classification of hepatocellular carcinoma (HCC), transarterial chemoembolization (TACE) may be offered as a treatment of palliative intent. We report the case of a patient suffering from acute respiratory distress syndrome after TACE with drug-eluting beads loaded with doxorubicin for HCC. To ou...

Over the past decade, irinotecan has become one of the first-line chemotherapeutic agents used in the treatment of metastatic colorectal cancer. Recently, irinotecan has been administered transarterially in order to perform chemoembolization in the liver. In the limited number of reports available to date using this approach, serious adverse effects have not yet been reported. In this paper, we...

Cryptogenic organizing pneumonia (COP) is an inflammatory lung disease involving the distal bronchioles, respiratory bronchioles, bronchiolar ducts, and alveolae. The etiology is usually unknown; however, there are several known causes and associated systemic diseases. Corticosteroid therapy is the best treatment option and the prognosis of COP is good, with recovery in up to 80% of patients. W...

The pathophysiologic complexity of hepatocellular carcinoma (HCC) and underlying hepatic cirrhosis, make optimal treatment choice a clinical challenge. The radical change in the treatment algorithm of patients with advanced unresectable HCC over the past 7 years, with the introduction of anti-angiogenic agents in patients with only preserved liver function reflect this challenge. Even though da...