The mechanical stimuli resulting from weight loading play an important role in mature bone remodeling. However, the effect of weight loading on the developmental process in young bones is less well understood. In this work, chicks were loaded with bags weighing 10% of their body weight during their rapid growth phase. The increased load reduced the length and diameter of the long bones. The ave...

Background: Fibrin(ogen) maintains inflammation in various disorders but has never been linked to cartilage damage rheumatoid arthritis (RA) or other forms of inflammatory arthritis. Objectives: To investigate the role fibrin deposition on integrity Methods: Fibrin knee was analyzed by immunohistochemistry RA patients and murine adjuvant-induced (AIA). In chondrocytes, fibrinogen expression ( F...

objective articular cartilage as an avascular skeletal tissue possesses limited capacity to heal. on the other hand, it is believed that the regeneration capacity of each tissue is largely related to its stem cell contents. little is known about the presence of mesenchymal stem cells in articular cartilage tissue. this subject is investigated in the present study. materials and methods articula...

The most common tumor of the eyelids is basal cell carcinoma. At this site, excision can be performed using Mohs micrographic surgery. Reconstruction of the upper or lower eyelids is a challenge due to their structural complexity and their important function. The eyelid has classically been divided into the anterior lamella, comprising skin, subcutaneous cellular tissue, and the orbicularis ocu...

1. An enzyme, “chondroitinase-ABC,” has been purified to apparent homogeneity from extracts of Proteus vulgaris, NCTC 4636, which was adapted on a medium containing chondroitin sulfate C. It has the following properties. (a) At pH 8, it degrades chondroitin sulfates A, B, and C at greater rates than chondroitin and hyaluronic acid. It does not attack keratosulfate, heparin, or heparitin sulfate...