نتایج جستجو برای: chromosome 10q

تعداد نتایج: 119424  

Journal: :Reports of biochemistry & molecular biology 2013
Aliakbar Rahbarimanesh Pupak Derakhshandeh-Peykar Amirhassan Barkhordari Reza Ebrahimzadeh-Vesal Soja Shamizadeh Kalkhoran

BACKGROUND Here we describe a new case of partial distal 10q trisomy in a 6-year-old Iranian girl from healthy parents with mental, growth, and psychomotor retardations. METHODS Additional clinical features include dysmorphic craniofacial features, microcephaly, bilateral hydronephrosis without heart problems, small and rotated low-set ears, bow-shaped mouth, abnormal teeth, short neck, and a...

Journal: :Journal of medical genetics 1995
C M Aalfs J M Hoovers M A Nieste-Otter M M Mannens R C Hennekam N J Leschot

We report on a girl with a partial duplication of the proximal part of the long arm of chromosome 10, confirmed by chromosome painting. The phenotypic findings are compared to those found in six other published cases with the same karyotype. Recognition of a specific partial proximal trisomy 10q syndrome seems to be possible, consisting of mild to moderate developmental delay, postnatal growth ...

Journal: :The British journal of ophthalmology 2011
H W Mensink J Vaarwater R J W de Keizer D de Wolff-Rouendaal C M Mooy A de Klein D Paridaens

BACKGROUND Uveal melanomas can develop in the choroid, ciliary body and iris. In choroidal and ciliary body melanomas, specific chromosomal changes correlate with metastatic disease. Iris melanomas have a better prognosis than choroidal melanomas, and it would be interesting to know if they share chromosomal changes. In addition, iris melanomas might harbour UV-induced mutations of tumour suppr...

Journal: :Journal of medical genetics 1990
K Ohba S Ohdo T Sonoda

A female infant with karyotype 46,XX,rec(10),dup p inv(10)(p11.2q25.2)mat is presented. She had both duplication of 10p and deletion of distal 10q, but only had the constellation of specific features characteristic of duplication of 10p.

2018
Michele Arigliani Luigi Castriotta Anna Pusiol Annachiara Titolo Enrico Petoello Alberto Brun Peressut Elisabetta Miorin Iana Elkina Federico Marzona Davide Cucchiaro Elisa Spanghero Matteo Pavan Raffaele Arigliani Stewart W Mercer Paola Cogo

BACKGROUND Empathy is a key element of "Patient and Family Centered Care", a clinical approach recommended by the American Academy of Pediatrics. However, there is a lack of validated tools to evaluate paediatrician empathy. This study aimed to validate the Visual CARE Measure, a patient rated questionnaire measuring physician empathy, in the setting of a Pediatric Emergency Department (ED). ...

Journal: :Human molecular genetics 2003
Yi-Ju Li Sofia A Oliveira Puting Xu Eden R Martin Judith E Stenger Clemens R Scherzer Michael A Hauser William K Scott Gary W Small Martha A Nance Ray L Watts Jean P Hubble William C Koller Rajesh Pahwa Mathew B Stern Bradley C Hiner Joseph Jankovic Christopher G Goetz Frank Mastaglia Lefkos T Middleton Allen D Roses Ann M Saunders Donald E Schmechel Steven R Gullans Jonathan L Haines John R Gilbert Jeffery M Vance Margaret A Pericak-Vance Christine Hulette Kathleen A Welsh-Bohmer

We previously reported genetic linkage of loci controlling age-at-onset in Alzheimer disease (AD) and Parkinson's disease (PD) to a 15 cM region on chromosome 10q. Given the large number of genes in this initial starting region, we applied the process of 'genomic convergence' to prioritize and reduce the number of candidate genes for further analysis. As our second convergence factor we perform...

2014
Yasser Al-Sarraj Hakam Abu Al-Khair Rowaida Ziad Taha Namat Khattab Zakaria H El Sayed Bushra Elhusein Hatem El-Shanti

KEY CLINICAL MESSAGE We report on a patient with distal trisomy 10q syndrome presenting with a few previously undescribed physical features, as well as, autism spectrum disorder (ASD). We recommend that patients with distal trisomy 10q syndrome should have a behavioral evaluation for ASD for the early institution of therapy.

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