Systemic sclerosis (SSc) is a chronic autoimmune multisystem disorder characterized by endothelialdysfunction and fibroblast dysfunction, which results in progressive fibrosis of the skin internalorgans more frequently lungs gastro intestinal tract. Pulmonary involvement common thecourse SSc, with Interstitial Lung Disease (ILD) Arterial Hypertension (PAH) alongwith pleural effusion being leadi...

The purpose of this investigation was to assess the effect of captopril on both systemic (P.a) and pulmonary arterial pressures (PPA) in patients with high-altitude pulmonary hypertension (HAPH). Seventeen patients (mean age 44±6.8 years) with HAPH and mild to moderate systemic arterial hypertension were included in the study. All patients underwent right heart catheterization with measurem...

Coronary hemodynamics are known to be affected by intravascular and extravascular factors that vary regionally and transmurally between the perfusion territories of left and right coronary arteries. However, despite clinical evidence that left coronary arterial dominance portends greater cardiovascular risk, relatively little is known about the effects of left or right dominance on regional con...

Chronic diseases with evidence for systemic arterial hypertension are one of the main causes mortality in country. The treatment these is done through allopathic medicines and medicinal plants, their association increasingly frequent thus also increases risk interactions. A literature review was carried out on implications use plants interaction drugs used to control hypertension, based works p...

223 Chronic liver diseases or liver injuries commonly result in increased intrahepatic resistance and subsequently lead to portal hypertension. Portal hypertension is associated with 2 distinct pathophysiologic features: hyper-dynamic circulation and formation of portal-systemic collaterals. 1 Hyperdynamic circulation is characterized by increased splanchnic blood flow, cardiac output, decrease...

Many pathological conditions, like sleep apnea (SA), preeclampsia, high altitude sickness, and chronic obstructive pulmonary disease, that cause intermittent or chronic hypoxia, are often associated with the development of either systemic or pulmonary hypertension. Mechanisms sensing hypoxia may be important contributors to the development of pulmonary hypertension and to tissue injury and repa...

introduction: chronic mountain sickness (cms) represents a syndrome of secondary polycythemia along with thrombocytopenia, altered hemorheology, pulmonary and systemic hypertension, and congestive heart failure, occurring due to hypobaric hypoxia-anoxia-induced erythropoiesis reported in both native mountain residents and new climbers after prolonged stays at high and extreme altitudes.case pre...

Definition of terms Pulmonary hypertension is defined as a mean pulmonary artery pressure > 25 mm Hg at rest or 30 mm Hg with exercise. The classification of pulmonary hypertension is linked to the anatomy or the aetiology. These diagnostic categories are for the convenience of deciding on treatment. Primary pulmonary hypertension refers to pulmonary hypertension for which no cause can be ident...