The circadian rhythm of COP23, a protein located in the cell membrane of Synechococcus RF-1, was regulated by a circadian synthesis rhythm and a circadian degradation rhythm. The circadian synthesis rhythm was controlled mainly at the transcriptional level (Chen et al., 1996). For the circadian degradation rhythm, some factors were responsible for COP23 degradation. The addition of chlorampheni...

Alterations of the circadian rhythms in blood pressure (BP) and heart rate (HR) have been associated with an increased cardiovascular disease risk. The influence of alcohol consumption on the circadian rhythm characteristics of BP is here examined, and the extent to which such alteration of the circadian BP rhythm contributes to cardiovascular disease

INTRODUCTION AND OBJECTIVES The aim of this study was to analyze the influence of modifiable cardiovascular risk factors on the circadian rhythm of acute myocardial infarction. PATIENTS AND METHOD We analyzed a retrospective cohort of 54,249 patients from a multicenter study of acute myocardial infarction (the Spanish ARIAM study). The variables were time of onset of symptoms, age, sex, previ...

In Drosophila multiple circadian oscillators and behavioral rhythms are known to exist, yet most previous studies that attempted to understand circadian entrainment have focused on the activity/rest rhythm and to some extent the adult emergence rhythm. Egg laying behavior of Drosophila females also follows circadian rhythmicity and has been seen to deviate substantially from the better characte...

Normal subjects with bipolarity phenotype, even though not diagnosed bipolar disorder, are known to show distinct properties. In this study, we investigate the changes in molecular circadian rhythm after bright light exposure before sleep in normal subjects with bipolarity phenotype. 25 young male subjects were divided to 14 for bipolarity group and 11 for nonbipolarity group after scoring of t...

Normal subjects with bipolarity phenotype, even though not diagnosed bipolar disorder, are known to show distinct properties. In this study, we investigate the changes in molecular circadian rhythm after bright light exposure before sleep in normal subjects with bipolarity phenotype. 25 young male subjects were divided to 14 for bipolarity group and 11 for nonbipolarity group after scoring of t...

Disruptions to circadian rhythm in mice and humans have been associated with an increased risk of obesity and metabolic syndrome. The gut microbiota is known to be essential for the maintenance of circadian rhythm in the host suggesting a role for microbe-host interactions in the regulation of the peripheral circadian clock. Previous work suggested a role for gut bacterial bile salt hydrolase (...

Cryptochrome (Cry) 1 and Cry2 are regarded as critical components for circadian rhythm generation in mammals. Nevertheless, cultured suprachiasmatic nucleus (SCN) of neonatal Cry double deficient (Cry1(-/-)/Cry2(-/-)) mice exhibit circadian rhythms that damp out in several cycles. Here, by combining bioluminescence imaging of Per1-luc and PER2::LUC with multielectrode recording, we show develop...

Endocrine biorhythms are classified according to the period time, as one of the most characteristic properties of biorhythms. Each endocrine organ has parallel more than one biorhythms with different period time (e. g. circadian and circannual rhythms). The time of acrophase of the biorhythms at the different endocrine organs is fairly variant. This review summarizes the rhythmic function of th...

Normal subjects with bipolarity phenotype, even though not diagnosed bipolar disorder, are known to show distinct properties. In this study, we investigate the changes in molecular circadian rhythm after bright light exposure before sleep in normal subjects with bipolarity phenotype. 25 young male subjects were divided to 14 for bipolarity group and 11 for nonbipolarity group after scoring of t...