Clefts are common birth defects. They are accompanied by various malformations, including disturbances in facial look as well as skeletal disorders that include malocclusions, most frequently crossbites and class III anomalies. The aim of the study was to present the commonest malocclusions in patients with total cleft of the lip, alveolar bone and palate (n = 154) and compare the results to th...

Background: One of the most common congenital malformations, with widespread racial and regional variation is an orofacial cleft. The occurrence attributed to array environmental genetic factors. Blood grouping Rh factor are genetically determined. Any possible association clefts them helps in planning interventional services. Methods: A case control observational study was conducted on 111 sam...

BACKGROUND AND PURPOSE Patients with vertebral fractures containing intraosseous clefts may represent a distinct subgroup of vertebroplasty patients, yet the development of subsequent vertebral fractures in this population has not been explored. We tested the hypothesis that after vertebroplasty for intraosseous clefts, subsequent fractures would occur earlier and more frequently than after tre...

PURPOSE To investigate factors that may influence successful correction of hypotony in a consecutive series of patients with cyclodialysis clefts repaired surgically over a 10-year period. DESIGN Retrospective interventional case series. METHODS Interventional case series of consecutive patients with cyclodialysis clefts and hypotony treated surgically after failure of conservative treatmen...

Laryngeal and laryngotracheal clefts are rare congenital malformations of the laryngobronchial tree. Their symptoms vary from mild cough to life threatening pulmonary aspiration and cyanosis. Type I and II clefts can be observed without surgical intervention, whereas type III and IV clefts usually require an anterior or lateral cervical approach. We present a case of type III laryngotracheal cl...

Accidental and nonaccidental spinal injuries are generally rarely seen in infants. If affected, vertebral bodies usually present compression fractures due to forced hyperflexion or hypertension. Radiographic examination of the infantile skeleton can reveal a radiolucent band running through a vertebral body. These so called vertebral clefts are mainly visualized in the lateral spinal radiograph...

Sapovirus (SaV) protease catalyzes cleavage of the peptide bonds at six sites of a viral polyprotein for the viral replication and maturation. However, the mechanisms by which the protease recognizes the distinct sequences of the six cleavage sites remain poorly understood. Here we examined this issue by computational and experimental approaches. A structural modeling and docking study disclose...

The shi...de construction in Mandarin Chinese is a cover term for at least four distinct constructions. We focus on the remarkable internal properties of the shi...de pattern proper, where both shi and de are present. We concur with a long tradition of scholarship identifying shi...de as a cleft construction, but we show it to have very different properties from itor pseudo-clefts in languages ...

Background: Patients with craniofacial clefts who have had reconstructive surgery often develop problems, such as contour deformity that will cause psychological issues. Micro and nano fat grafting are various methods utilized to overcome these Case Operation Technique: This case series describes two patients facial deformities due Tessier 3 4 clefts, respectively. Each patient underwent second...