clinical practice guidelines are the most important and valid guidelines for treatment of diseases, and are developed through experts consensus on a subject, considering the highest available evidence (systematic reviews, meta-analyses, and randomized controlled trials). we briefly review the latest evidence-based guidelines for the treatment of two common diseases of acne (provided by european...

conclusions along with adaptation and development process of cpgs, their utilization should also be planned; otherwise spent time and money would be in vain. certainly, imposing above-mentioned interventions with the ultimate goal of sustainable behavior change in health system service providers is beyond the capacity of specific groups or few academic centers. it requires the participation of ...

Objective: To provide an updated guideline for the surgical and medical termination of pregnancy. Options: This guideline discusses and compares the safety and effectiveness of currently available pregnancy termination procedures. Outcomes: To provide safe and effective methods for the termination of pregnancy. Evidence: The Medline, EMBASE, and Cochrane databases were searched for relevant art...

In clinical practice guidelines (CPGs) the medical information is stored in a narrative way. A large part of this information occurs in a negated form. The detection of negation in CPGs is an important task since it helps medical personnel to identify not occurring symptoms and diseases as well as treatment actions that should not be accomplished. We developed algorithms capable of Negation Det...