نتایج جستجو برای: clonal population
تعداد نتایج: 714788 فیلتر نتایج به سال:
Accurate inferences on population genetics data require a sound underlying theoretical null model. Organisms alternating sexual and asexual reproduction during their life-cycle have been largely neglected in theoretical population genetic models, thus limiting the biological interpretation of population genetics parameters measured in natural populations. In this article, we derive the expectat...
Our objective was to analyze the evolution of resistance mutations (RM) and viral tropism of multi-drug-resistant (MDR) strains detected at primary HIV-1 infection (PHI). MDR HIV strain was defined as the presence of genotypic resistance to at least 1 antiretroviral of the 3 classes. Tropism determinations (CCR5 or CXCR4) were performed on baseline plasma HIV-RNA and/or PBMC-HIV-DNA samples, th...
The prevalence of anaphylaxis among patients with clonal mast cell disorders (MCD) is clearly higher comparing to the general population. Due to a lower frequency of symptoms outside of acute episodes, clonal MCD in the absence of skin lesions might sometimes be difficult to identify which may lead to underdiagnosis, and anaphylaxis is commonly the presenting symptom in these patients. Although...
to improve commercial grapevine cultivars, it is necessary to apply such methods that by cultivation of a certain number of vines in a certain area, higher yield could be harvested. to achieve such a goal, healthy stocks with resistant to pests and diseases, high fructification and high quality of vines are needed. all these properties can be obtained successfully through clonal selection. viti...
Toxoplasma gondii has been described as a parasite with a low genetic diversity and a clonal population structure. The three main clonal lineages designated as type I, II or III largely predominate in Europe and North America. But strains not related to these main lineages circulate, notably, in other continents. They possess a shuffled combination of alleles that typify the three clonal types ...
The dynamics of genetic diversity in large clonally-evolving cell populations are poorly understood, despite having implications for the treatment of cancer and microbial infections. Here, we combine barcode lineage tracking, sequencing of adaptive clones, and mathematical modelling of mutational dynamics to understand diversity changes during experimental evolution. We find that, despite diffe...
The traditional single clonal selection algorithm has a lot of disadvantages, for example, it is easy to be trapped into local optima, and it has a lot of massive redudacy iteration in its later period and inferior global search ability and so on. In this paper, a new artificial immune algorithm is proposed based on the clonal selection theory and the structure of anti-idiotype(IAAI), which is ...
Tea (C. sinensis L.) is the most important beverage crop in Iran and genetic base of current Iranian tea shrubs were achieved from three mass seeds namely: Dhongan, Batjan and Raighur. In this study, genetic diversity of 30 cultivated tea clones were evaluated using 45 RAPD markers and 13 morphological and 4 chemical characters respectively. Sixteen and of 45 markers produced 96 bands that 89 b...
BACKGROUND Serotype 19A invasive pneumococcal disease (IPD) increased annually in the United States after the introduction of the 7-valent conjugate vaccine (PCV7). To understand this increase, we characterized serotype 19A isolates recovered during 2005. METHODS IPD cases during 1998-2005 were identified through population-based surveillance. We performed susceptibility testing and multilocu...
The methicillin-resistant Staphylococcus aureus (MRSA) clonal group known as ST239-MRSA-III is notable for its hybrid origin and for causing sustained hospital epidemics worldwide since the late 1970s. We studied the population structure of this MRSA clonal group using a sample of 111 isolates that were collected over 34 years from 29 countries. Genetic variation was assessed using typing metho...
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