ETHNOPHARMACOLOGICAL RELEVANCE The stem bark of Garcinia livingstonei is used traditionally as a skin lightening agent. AIM OF THE STUDY To isolate and identify compounds responsible for the observed skin lightening activity of Garcinia livingstonei and to evaluate their cytotoxicity. MATERIALS AND METHODS Constituents of the stem bark and fruits of Garcinia livingstonei were isolated using...

Calophyllum brasiliense (Clusiaceae/Guttiferae) is a native Brazilian medicinal plant traditionally used against several diseases, including infectious pathologies. Crude methanolic extracts (CME) and two fractions, denoted non-polar (soluble in chloroform) and polar (nonsoluble in chloroform), were prepared from different parts of the plant (roots, stems, leaves, flowers and fruits) and studie...

O presente trabalho teve como objetivo reunir, sistematizar e discutir os mais recentes estudos que abordam sobre compostos bioativos e/ou as propriedades funcionais biológicas de espécies vegetais cultivadas no Brasil. A maioria dos envolveram famílias Anacardiaceae, Arecaceae, Annonaceae, Apocynaceae, Caryocaraceae, Clusiaceae, Fabaceae, Malpighiaceae, Myrtaceae Rubiaceae, Oxalidaceae, Olacac...

Three new 4-phenylcoumarins, mesuaferlinns A–C (1–3), together with ten other known 4–13, were isolated from the branches and leaves of Mesua ferrea Linn. (Clusiaceae). The structure compounds 1–3 determined on basis spectroscopic methods including extensive analysis NMR mass data. Ten 4-phenylcoumarins tested for their cytochrome P450 family 1 enzymes (CYP1A1, CYP1A2, CYP1B1) inhibitory effect...