OBJECTIVE Coagulation factor VIIa (VIIa) binding to its cellular receptor, tissue factor (TF), not only initiates the coagulation cascade but also induces cell signaling by activating G-protein coupled protease-activated receptors. The objective of the present study is to investigate the role of lipid rafts and caveolae in modulating TF-VIIa signaling and coagulant functions. METHODS AND RESU...

Conventional coagulation is not an effective treatment option to remove natural organic matter (NOM) in water with high alkalinity/pH. For this type of water, enhanced coagulation is currently proposed as one of the available treatment options and is implemented by acidifying the raw water and applying increased doses of hydrolyzing coagulants. Both of these methods have some disadvantages such...

Inorganic aluminum or iron salts have been used for many decades to coagulate colloidal particles in surface water prior to flocculation, sedimentation and/or filtration. Although effective, inorganic coagulants have several disadvantages including large chemical dosages required for treating eutrophic waters, large volumes of chemical sludge produced, and toxic effects of metallic coagulants o...

The processes of coagulation and flocculation using high molecular weight long-chain polymers were applied to treat mine water having fine flocs of which about 93% of the total mass was less than 3.02 microm, representing the size distribution of fine particles. Six different combinations of acryl-type anionic flocculants and polyamine-type cationic coagulants were selected to conduct kinetic t...

colloids are small suspended particles in water which can not be settled or removed naturally due to their light weight and stability. these particles pose some degree of stability and cause water turbidity. there are some concerns regarding colloid removal efficiency in water treatment plants of iran. in this study, the effectiveness of aluminium sulfate and poly-aluminum chloride was evaluate...

introduction: colloidal materials and suspended solids cause turbidity in water. to remove turbidity, clarification method is used that includes processes of coagulation, flocculation, and sedimentation. due to the long duration of coagulation process, coagulant aids are applied. despite the favorable efficiency of synthetic polyelectrolytes as a coagulant aid, due to their harmful effects on h...

One of the industrial areas in the south of Iran is Bandar Imam Petrochemical Economic Zone which has a lot of petrochemical complex, Farabi Petrochemical complex is one of those places. Coagulation/flocculation could be a typical methodology in water and wastewater treatment that a number of chemicals are added to assist the coagulation/flocculation and causes to the sedimentation. In this pap...

INTRODUCTION Multiple sclerosis (MS) is a chronic demyelinating inflammatory disease of the central nervous system (CNS) affecting prevalently young adults (1, 2). The pathogenesis of MS has long been attributed to self-reactive T cells but recently the relevant role of B cells has also been recognized (2, 3). Furthermore, it has been demonstrated that innate immunity has a pivotal role in the ...

Artificial Neural Network (ANN) techniques are applied to the control of coagulant dosing in a drinking water treatment plant. Coagulant dosing rate is non-linearly correlated to raw water parameters such as turbidity, conductivity, pH, temperature, etc. An important requirement of the application is robustness of the system against erroneous sensor measurements or unusual water characteristics...

Coagulant dosing control in drinking and wastewater treatment plants (WWTPs) is often limited to flow proportional concepts. The advanced multi-parameter-based dosing control systems have significantly reduced coagulant consumption and improved outlet qualities. Due to the long retention time in separation stages, these models are mostly based on feed-forward (FF) models. This paper demonstrate...