BACKGROUND Although stem cell therapy has provided a promising treatment for myocardial infarction, the low survival of the transplanted cells in the infarcted myocardium is possibly a primary reason for failure of long-term improvement. Therefore, the development of novel prosurvival strategies to boost stem cell survival will be of significant benefit to this field. METHODS AND RESULTS Card...

Objective(s): In this study, a cocktail of probe drugs was used to assess whether lentinan could influence the activities of rat enzymes CYP3A4, CYP2D6, CYP1A2, CYP2C19, and CYP2C9 in vivo. Materials and Methods: Fourteen days after intraperitoneal injection of lentinan, rats were given an oral dose of a cocktail solution containing phenacetin, tolbutamide, omeprazole, metoprolol, and midazolam...

We present a new approach to the cocktail party problem that uses a cortronic artificial neural network architecture (Hecht-Nielsen, 1998) as the front end of a speech processing system. Our approach is novel in three important respects. First, our method assumes and exploits detailed knowledge of the signals we wish to attend to in the cocktail party environment. Second, our goal is to provide...

The seroreactivity of a cocktail of purified mycobacterial excretory–secretory (ES) antigens ES-31, ES-41 and ES43 was assessed by ELISA and immunoblotting in patients with pulmonary tuberculosis. The ES-31 antigen was isolated by affinity chromatography and ES-41 and ES-43 were isolated by fast protein liquid chromatography from Mycobacterium tuberculosis H37Ra culture filtrate. Seven of 27 pu...

A 35-year-old woman was admitted after a sudden left-arm deficit, which was preceded by 3 weeks of the same transient episodes lasting less than 5 minutes each. She was being treated for menorrhagia with tranexamic acid and was also using oral contraceptives. Three weeks before, she had a Mycoplasma pneumoniae respiratory infection. MRI showed a recent ischemia in the territories of the right m...

In cocktail party listening scenarios, the human brain is able to separate competing speech signals. However, the signal processing implemented by the brain to perform cocktail party listening is not well understood. Here, we trained two separate convolutive autoencoder deep neural networks (DNN) to separate monaural and binaural mixtures of two concurrent speech streams. We then used these DNN...

Recent mobile devices are capable of creating and storing a large amount of multimedia data, but sharing those data with others is still challenging. This paper presents Cocktail, a new gesture-based mobile interaction system that exploits bartenders’ motions. Like a bartender who pours drinks to a glass, a user can pour (transfer) multimedia data to other device. The user can also mix music fi...

The World Health Organization estimates human mortality from endemic canine rabies to be 55,000 deaths/year. Limited supply hampers the accessibility of appropriate lifesaving treatment, particularly in areas where rabies is endemic. Anti-rabies antibodies are key to protection against lethal rabies. Currently, only human and equine polyclonal anti-rabies immune globulin (HRIG and ERIG) is avai...

African Swine Fever Virus (ASFV) is a high-consequence transboundary animal pathogen that often causes hemorrhagic disease in swine with a case fatality rate close to 100%. Lack of treatment or vaccine for the disease makes it imperative that safe and efficacious vaccines are developed to safeguard the swine industry. In this study, we evaluated the immunogenicity of seven adenovirus-vectored n...

AIM To describe birthing outcomes among women who consumed castor oil cocktail as part of a freestanding birth center labor induction protocol. METHODS De-identified data from birth logs and electronic medical records were entered into SPSS Statistics 22.0 for analysis for all women who received the castor oil cocktail (n=323) to induce labor between January 2008 and May 2015 at a birth cente...