نتایج جستجو برای: coefficient cα

تعداد نتایج: 170285  

2011
Odalric-Ambrym Maillard Rémi Munos

In this document, we detail further some technical proofs not covered in the paper corresponding to this supplementary material. 1 Playing against an opponent using a known model 1.1 Regret upper bounds against the best history-class-based strategy Theorem 1 In the case of a Φ-constrained opponent, using the Φ-UCB algorithm with parameter α > 1/2, we have the distribution-dependent bound: R T ≤...

Journal: :Journal of Biological Chemistry 1996

2012
Yaman Arkun Mert Gur

A new method to develop low-energy folding routes for proteins is presented. The novel aspect of the proposed approach is the synergistic use of optimal control theory with Molecular Dynamics (MD). In the first step of the method, optimal control theory is employed to compute the force field and the optimal folding trajectory for the Cα atoms of a Coarse-Grained (CG) protein model. The solution...

2001
T. Kent Kirk

The author reviews the use of dimeric model compounds (two aromatic nuclei) in investigations of the degradation of lignin by white-rot fungi, and compares the results of such studies with those obtained using l i g n i n i t s e l f . Findings are summarized for the four types of compounds that have been studied: a) Phenolic β-O -4 and β-5 mode1 compounds are invariably oxidized in cultures by...

2015
Reetu Sharma G. Narahari Sastry Sabato D'Auria

Thermus thermophilius isopropylmalate dehydrogenase catalyzes oxidative decarboxylation and dehydrogenation of isopropylmalate. Substitution of leucine to alanine at position 172 enhances the thermal stability among the known point mutants. Exploring the dynamic properties of non-covalent interactions such as saltbridges, hydrogen bonds and hydrophobic interactions to explain thermal stability ...

2014
Ping Li Cun-Hui Zhang Tong Zhang

Compressed1 sensing (sparse signal recovery) has been a popular and important research topic in recent years. By observing that natural signals are often nonnegative, we propose a new framework for nonnegative signal recovery using Compressed Counting (CC). CC is a technique built on maximally-skewed α-stable random projections originally developed for data stream computations. Our recovery pro...

Journal: :The Journal of biological chemistry 2011
Jianhua Shi Wei Qian Xiaomin Yin Khalid Iqbal Inge Grundke-Iqbal Xiaosong Gu Fei Ding Cheng-Xin Gong Fei Liu

Hyperphosphorylation and deposition of tau into neurofibrillary tangles is a hallmark of Alzheimer disease (AD). Alternative splicing of tau exon 10 generates tau isoforms containing three or four microtubule binding repeats (3R-tau and 4R-tau), which are equally expressed in adult human brain. Dysregulation of exon 10 causes neurofibrillary degeneration. Here, we report that cyclic AMP-depende...

2017
Zheng-Hang Qi Yi Zhang Yun Gao Ye Zhang Xing-Wang Wang Yong Wang

The origin of the enantio- and regioselectivity of ring-opening reaction of oxabicyclic alkenes catalyzed by rhodium/Josiphos has been examined using M06-2X density functional theory(DFT). DFT calculations predict a 98% ee for the enantioselectivity and only the 1,2-trans product as one regio- and diastereomer, in excellent agreement with experimental results. The solvent tetrahydrofuran(THF) p...

2017
Jakub Adamek Roman Mazurkiewicz Anna Węgrzyk Karol Erfurt

An effective synthesis of the hitherto unknown 1-imidoalkylphosphonium salts has been developed in the reported study. The crucial step in the method included the decarboxylative α-methoxylation of N-phthaloyl- or N-succinylamino acids to the corresponding N-(1-methoxyalkyl)imides, followed by the displacement of the methoxy group by the triarylphosphonium group through melting of the imide der...

2006
Stefan Canzar Jan Remy

In this paper we describe a similarity model that provides the objective basis for clustering proteins of similar structure. More specifically, we consider the following variant of the protein-protein similarity problem: We want to find proteins in a large database D that are very similar to a given query protein in terms of geometric shape. We give experimental evidence, that the shape similar...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید