Coffee consumption reduces the risk of type 2 diabetes in humans, but the mechanism remains unclear. In this study, we investigated the effect of coffee on pancreatic β-cells in the induction of diabetes by streptozotocin (STZ) treatment in mice. We examined the effect of coffee, caffeine, or decaffeinated coffee ingestion on STZ-induced hyperglycemia. After STZ injection in Exp. 1 and 2, serum...

The objective of this study was to determine the pharmacokinetics of caffeine after single administration of a coffee enema versus coffee consumed orally in healthy male subjects. The study design was an open-label, randomized two-phase crossover study. Eleven healthy subjects were randomly assigned either to receive 500 mL of coffee enema for 10 minutes or to consume 180 mL of ready-to-drink c...

Climate change will cause geographic range shifts for pollinators and major crops, with global implications for food security and rural livelihoods. However, little is known about the potential for coupled impacts of climate change on pollinators and crops. Coffee production exemplifies this issue, because large losses in areas suitable for coffee production have been projected due to climate c...

THE PRINCIPAL OBJECTIVE OF THIS STUDY WAS TO ASSESS THE INSTRUMENTAL AND SENSORY CHARACTERISTICS OF GINSENG COFFEE WITH DIFFERENT RATIOS OF THE INGREDIENTS: type of coffee bean (Colombia, Brazil, and Indonesia), type of ginseng extract (white ginseng, red ginseng, and America ginseng) and concentration of ginseng extract (3, 6, and 9 w/v %). The sensory optimal condition of white ginseng coffee...

8.30—9.05 8.30—9.05 8.30—9.05 8.30 – 9.05 8.15 – 8.50 9.05 – 9.40 Otto 9.05 – 9.40 9.05 – 9.40 9.05 – 9.40 8.50 – 9.25 9.25 – 10.00 Li 09.40 –10.10 Coffee 09.40 –10.10 Coffee 09.40 –10.10 Coffee 09.40 –10.10 Coffee 10.00 – 10.30 Coffee 10.10 – 10.35 10.10 – 10.35 10.10 – 10.45 10.10 – 10.45 10.35 – 11.10 10.35 – 11.00 10.45 – 11.10 10.45 – 11.10 10.30 – 10.55 Weber 11.10 – 11.35 11.00 – 11.25 1...

Cultural heritage relics in an area are historical evidence that need to be maintained and preserved. The cultural reserve found Toweren Uken the form of traditional house King Baluntara (wilderness). Its existence provided information regarding formation kingdom 18th century Central Aceh. king’s residence is a on stilts decorated with several typical Gayo openwork ornament. Inside it built sev...

BACKGROUND Coffee consumption has been reported to be inversely associated with risk of type 2 diabetes mellitus. Similar associations have also been reported for decaffeinated coffee and tea. We report herein the findings of meta-analyses for the association between coffee, decaffeinated coffee, and tea consumption with risk of diabetes. METHODS Relevant studies were identified through searc...

R-Coffee is a multiple RNA alignment package, derived from T-Coffee, designed to align RNA sequences while exploiting secondary structure information. R-Coffee uses an alignment-scoring scheme that incorporates secondary structure information within the alignment. It works particularly well as an alignment improver and can be combined with any existing sequence alignment method. In this work, w...

BACKGROUND Coffee is the most abundantly consumed stimulant worldwide. However, its cardiovascular safety remains controversial. Possible health hazards have been related to its main ingredient, caffeine. Activation of the sympathetic nervous system by coffee may enhance cardiovascular risk; however, it is unclear whether this effect of coffee is related to caffeine or other substance(s) also c...

There is plausible biological evidence as well as epidemiologic evidence to suggest coffee consumption may lower endometrial cancer risk. We evaluated the associations between self-reported total coffee, caffeinated coffee and decaffeinated coffee, and endometrial cancer risk using the Women's Health Initiative Observational Study Research Materials obtained from the National Heart, Lung, and B...