Background: The SALL4/Sall4 is constitutively expressed in human and mice. SALL4 mRNA could be used as a marker for the diagnosis of different types of cancers. On the other hand, chrysin has diverse biological properties. Objectives: In the present study, the effect of the chrysin was investigated on the CT26 colon cancer in vitro and in vivo. Furthermore, the expression levels of the stem cel...

objective(s):sea cucumber is one of the classes of echinoderms, which is considered as a health marine product and possess various biological characteristics with therapeutic application. the present investigation attempted to evaluate the potential of anti-cancer persian gulf sea cucumber species holothuria arenicola (h. arenicola) aqueous extract on mice colon carcinoma cells in vitro and in ...

background: early diagnosis and endoscopic resection of adenomatous polyps is the main approach for screening and prevention of colorectal cancer (crc). we aimed to assess polyp detection rate (pdr) and to characterize demographic, clinical, and pathological features of colorectal polyps in an iranian population. methods: we retrospectively analyzed the data from 5427 colonoscopies performed du...

conclusions traf6 plays an important role in the onset of colon cancer; therefore, drugs targeting it may have great clinical significance in the treatment of this disease. results the positive expression rate of traf6 in tumor tissues was 66.7%, which was significantly higher than in normal paracancerous tissues (18.5%). the positive expression rate of traf6 was significantly correlated with d...

Background: Recent evidence suggests that regular exercise training is effective in treating various aspects of cancer. Therefore, the purpose of this study was to determine the effect of 8 weeks of aerobic interval training on monocarboxylate transporter 1 (MCT1) protein and expression of p53 gene in tumor of colon cancer mice. Methods: The present study was conducted experimentally from May ...

colonoscopy overview — a colonoscopy is an exam of the lower part of the gastrointestinal tract, which is called the colon or large intestine (bowel). colonoscopy is a safe procedure that provides information other tests may not be able to give. colonoscopy is performed by inserting a device called a colonoscope into the anus and advanced through the entire colon. the procedure generally takes ...

background: clinical and epidemiological variation was seen between the colon cancer (cc) and rectum cancer (rc). so, there is not so much data available about the epidemiological and clinicopathological differences and prognostic factors regarding to cc and cr in iran, we aimed to perform this study. methods: all cases of cc and rc referred to oncology and gastroenterology wards of taleghani g...

Background & Objectives: Colon cancer is currently of high incidence and mortality rate. Identifying the factors influencing its prognosis can be very beneficial to its clinical treatment. Recent studies have shown that lymph nodes ratio can be considered as an important prognostic factor. The aim of the present study is to investigate the effect of this factor on the prognosis of the ...

dear editors: adenocarcinoma of colon and rectum is the second most common cancer of the gastrointestinal (gi) tract in children. the development of carcinoma of colon in general appears to be associated with several predisposing factors such as familial polyposis, hereditary non-polyposis syndromes, ulcerative colitis, previous ureterosigmoidostomy or radiation therapy and dietary factors (hig...