Colorectal Cancer (CRC) is the second most common cancer in women and third men. There strong evidence for role of Stem Cells (CSCs) progression. The identification understanding CSCs genes such as LGR5 involved induction development crucial prognosis CRC. a membrane protein several molecular signaling pathways, Wnt NOTCH pathways. It has been shown that gene was overexpressed CRC associated wi...

Background and Objective: Colorectal cancer (CRC) is one of the most prevalent malignancies in the world. The early detection of CRC is not only a simple process, but it is also the key to its treatment. Given that data mining algorithms could be potentially useful in cancer prognosis, diagnosis, and treatment, the main focus of this study is to measure the performance of some data mining class...

In the Western world, colorectal cancer (CRC) is the third most common cancer with poor prognosis. To identify the proteins and to elucidate the possible mechanisms involved in colorectal carcinogenesis, 2-DE coupled with MS/MS analysis were employed to compare the global protein profile between CRC and individual matched normal tissues from 8 CRC patients. Of 36 proteins identified, carbonic a...

The study objective : the is to examine use of artificial intelligence (AI) in diagnosis, treatment, and prognosis Colorectal Cancer (CRC) discuss future potential AI CRC. Material Methods . Web Science, Scopus, PubMed, Medline, eLIBRARY databases were used search for publications. A on application Artificial Intelligence was discovered more than 100 sources. In review, data from 83 articles in...

Colorectal cancer (CRC) is the third most common cancer disease. Here we examined Nampt expression in patients with CRC and the effect of Nampt on cell viability in CRC cells. Nampt protein was overexpressed in colorectal adenoma as well as colorectal carcinoma. The immunoreactive staining of Nampt was negative in the adjacent normal colorectal tissue, weak in colorectal adenoma, and strong in ...

Introduction For several years, the link between colorectal cancer (CRC) and exercise has been widely investigated [1]; with observational findings suggesting that physical activity (PA) is associated a disease-specific higher overall survival in those CRC [2]. In an early meta-analysis of six prospective cohort studies

abstract:   introduction: colorectal cancer (crc) is one of the most common cancers in the world. during the past decades, survival of colorectal cancer patients has improved worldwide, however, it is not clear what factors have contributed to this development. this study was designed to evaluate the prognostic impact of a wide spectrum of pathologic parameters on survival rate in patients with...

background: cancer is the third most common cause of death in iran. gastric cancer (gc) and colorectal cancer (crc) are two important causes of mortality due to cancer. with regards to cancer mortality, data are important to monitor the effects of screening program, earlier diagnosis, demographic data and other prognostic factors. the aim of this study was to evaluate the mortality rates and tr...

The TP53-induced glycolysis and apoptosis regulator (TIGAR) is a p53 target gene known to regulate glycolysis by acting as fructose bis-phosphatase (FBPase) and modulate reactive oxygen species. TIGAR expression has been implicated in oncogenesis and progression of several human cancers. However, TIGAR expression is not known in various stages of colorectal cancer (CRC). There is an increase in...