Technique for Order preference by Similarity to Ideal Solution (TOPSIS) is a Multi Attribute DecisionMaking (MADM) technique employed in diverse disciplines for the prioritization of alternative options/solutions to a problem. Test vector compaction for analog fault detection is a field which is witnessing continuous growth and experimentation. This study suggests a novel TOPSIS-based approach ...

Human telomeres consist of thousands of base pairs of double-stranded TTAGGG repeats, organized by histone proteins into tightly spaced nucleosomes. The double-stranded telomeric repeats are also specifically bound by the telomeric proteins hTRF1 and hTRF2, which are essential for telomere length maintenance and for chromosome protection. An unresolved question is what role nucleosomes play in ...

Nucleoid-associated proteins (NAPs) facilitate chromosome organization in bacteria, but the precise mechanism remains elusive. H-NS is a NAP that also plays a major role in silencing pathogen genes. We used genetics, single-particle tracking in live cells, superresolution microscopy, atomic force microscopy, and molecular dynamics simulations to examine H-NS/DNA interactions in single cells. We...

this research was performed to investigate the combined effect of soil salinity and compaction on some physiological characteristics of corn. for this purpose a factorial pot experiment on the basis of completely randomized design with three replications was performed. the experimental factors were three levels of soil salinity (saturated paste extract electrical conductivity 1.5, 2.5 and 4.5 d...

The interaction of cationic surfactants with single dsDNA molecules has been studied using force-measuring optical tweezers. For hydrophobic chains of length 12 and greater, pulling experiments show characteristic features (e.g. hysteresis between the pulling and relaxation curves, force-plateau along the force curves), typical of a condensed phase (compaction of a long DNA into a micron-sized ...

Hfq is a bacterial protein that is involved in several aspects of nucleic acids metabolism. It has been described as one of the nucleoid associated proteins shaping the bacterial chromosome, although it is better known to influence translation and turnover of cellular RNAs. Here, we explore the role of Escherichia coli Hfq's C-terminal domain in the compaction of double stranded DNA. Various ex...

Microsporidia have been known for some time to possess among the smallest genomes of any eukaryote. There is now a completely sequenced microsporidian genome, as well as several other large-scale sequencing efforts, so the nature of these genomes is becoming apparent. This paper reviews some of the characteristics of microsporidian genomes in general, and some of the recent discoveries made thr...

Methods of preparing test specimens in laboratories are particularly important. It also holds true in terms of compaction procedure in predicting pavement performance. The currently available laboratory compactor cannot adequately replicate field compaction conditions, especially the Stone Mastic Asphalt (SMA) mixture. The essential element of SMA mixture comprises of stones that are placed nex...