To determine the influence of renal failure on the pharmacokinetics and neuromuscular blockade of Org NC 45 (Norcuron), a new monoquaternary homologue of pancuronium, 13 patients under halothane and nitrous oxide anesthesia were studied. Org NC 45 was administered by 2-min infusion in doses of 0.28 mg kg-1 (normal renal function group, n = 4) and 0.14 mg kg-1 (renal failure group, n = 5). Four ...

bioretention or rain garden is a preferable low impact development (lid) approach due to its characteristics which reflect natural water cycle processes. however, this system is still little understood and quite complicated in terms of design and implementation due to many technical considerations. hence, this paper gives a review of the challenges and developments for the use of bioretention f...

nowadays, environment-sensitive smart drug delivery systems have found diverse applications in pharmaceutical science and technology. these systems can respond to the environment stimuli such as temperature, pressure, ph, light, electrical and magnetical fields and etc. they can release the proper amount of drug in human body. among these systems, special attention and much research works have ...

Two-dimensional polynomial dynamical systems are mainly considered. We develop Erugin’s two-isocline method for the global analysis of such systems, construct canonical systems with field-rotation parameters and study various limit cycle bifurcations. In particular, we show how to carry out the classification of separatrix cycles and consider the most complicated limit cycle bifurcation: the bi...

  Objective(s): Appendicitis remains the most common condition in the pediatric population requiring emergency abdominal operation. Management of acute simple appendicitis is well described but controversy remains as to the optimal treatment of complicated appendicitis. Common complications of acute appendicitis include: localized peritonitis and abscess formation, flegmon and general perito...

Distributed systems such as Grid- and Cloud Computing provision web services to their users in all of the world. One of the most important concerns which service providers encounter is to handle total cost of ownership (TCO). The large part of TCO is related to power consumption due to inefficient resource management. Task scheduling module as a key component can has drastic impact on both user...