Impulsive-compulsive behaviours are a significant source of morbidity for patients with Parkinson's disease receiving dopaminergic therapy. The development of these behaviours may reflect sensitization of the neural response to non-drug rewards, similar to that proposed for sensitization to drug rewards in addiction. Here, by using (11)C-raclopride positron emission tomography imaging, we inves...

BACKGROUND Overactive bladder syndrome is characterized by urinary urgency, usually accompanied by Frequent urination and nocturia, with or without urgent urinary incontinence. There must be the absence of causative infection or pathological conditions. Overactive bladder syndrome is related to mental disorders, particularly depression and anxiety. However, obsessive-compulsive symptoms are inv...

A previous analysis of the quinpirole sensitisation rat model of obsessive-compulsive disorder revealed that the behavioral phenotype of compulsive checking consists of three constitutive components - vigor of checking performance, focus on the task of checking, and satiety following a bout of checking. As confirmation of this analysis, the aim of the present study was to reconstitute, without ...

OBJECTIVE To update clinicians regarding the existence of a putative subtype of obsessive-compulsive disorder based on poor insight. METHOD Opinionative review based on studies indexed in the PubMed and PsychINFO databases, identified by means of the keywords 'obsessive-compulsive disorder' AND 'insight' OR 'ego-syntonic', and published between 1966 and October 2009. The results were analyzed...

Although a growing body of literature addresses the effects of young people's use of sexually explicit Internet material, research on the compulsive use of this type of online content among adolescents and its associated factors is largely lacking. This study investigated whether factors from three distinct psychosocial domains (i.e., psychological well-being, sexual interests/behaviors, and im...

In the signal attenuation rat model of obsessive-compulsive disorder, 'compulsive' behavior is induced by attenuating a signal indicating that a lever-press response was effective in producing food. In recent years several studies have reported that Lewis rats, an inbred strain derived from the Sprague Dawley strain, exhibit addictive and/or compulsive tendencies. The aim of the present study w...

To investigate the role of the nucleus accumbens core (NAc) in the development of quinpirole-induced compulsive checking, rats received an excitotoxic lesion of NAc or sham lesion and were injected with quinpirole (0.5 mg/kg) or saline; development of checking behavior was monitored for 10 biweekly tests. The results showed that even after the NAc lesion, quinpirole still induced compulsive che...

Background and aims The addictive nature of compulsive buying implies that mood disturbances, stress, and cognitive biases that underlie compulsive buying might operate in ways similar in both genders. In the current study, we aimed to test hypothetical pathways of mood compensation and irrational cognitions, which may explain compulsive buying tendencies. We also examined potential gender diff...

BACKGROUND AND AIMS Descriptions of compulsive buying often emphasize the roles of negative moods and trait impulsivity in the development of problematic buying habits. Trait impulsivity is sometimes treated as a unidimensional trait in compulsive buying research, but recent factor analyses suggest that impulsivity consists of multiple components that are probably best treated as independent pr...

In spite of a hundred year long history of scientific research compulsive buying has been a hardly known phenomenon until today. Ambiguous scientific information makes it impossible to classify compulsive buying as a separate mental disorder. Recently many researchers have noticed phenomenological compatibility of compulsive buying with behavioural addictions. Nowadays, there is reasonable grou...