Obsessive Compulsive Disorder (OCD) is an anxiety disorder, characterized by repetitive unwanted obsessions and compulsions, with a prevalence of 0.5-1% to 4% in childhood and adolescence. The exact pathogenesis of OCD remains uncertain but multiple components such as hereditary/genetic, cognitive, biological, environmental and behavioral factors have been implicated. The aim of this review is ...

Investigations of memory and associated phenomena in obsessive-compulsive disorder (OCD) can advance our understanding of this often debilitating problem. Theoretical models predict both the presence and absence of memory biases in favour of threat-relevant information in association with anxiety disorders generally, and with OCD specifically. Two previous experiments (one involving compulsive ...

Introduction Obsessive-compulsive disorders are complex pathologies causing a major psychosocial handicap. However, their association with disabling somatic pathology such as rheumatoid arthritis makes management more difficult. Objectives To investigate through case analysis and review of literature the between obsessive-compulsive disorder (OCD) rheumatological disorders. Methods We reported ...

We assessed correlates of obsessive-compulsive (OCPD), schizotypal (SPD) and borderline (BPD) personality disorders in 110 obsessive-compulsive disorder (OCD) patients. We found OCD patients with OCPD (20.9%) to exhibit higher rates of hoarding and bipolar disorders, increased severity of hoarding and symmetry, lower prevalence of unacceptable thoughts involving sex and religion and less non-pl...

introduction: comorbid obsessive-compulsive disorder (ocd) has been reported among patients with schizophrenia in other countries. but, the literature is not well-documented on this issue in iran (persia). the present study aimed to investigate the prevalence and severity of ocd and some of its related factors in a group of patients with schizophrenia in iran.  methods: this is a cross-sectiona...

Glutamatergic hyperactivity hypothesis in obsessive-compulsive disorder (OCD) has been proposed but not tested. Memantine is an uncompetitive N-methyl-d-aspartate (NMDA) receptor antagonist. We report two cases of refractory obsessive-compulsive disorder treated with an augmentation of memantine at 15 mg/day. The first case did not benefit from such treatment, while the second showed immediate ...

An association between epilepsy and obsessive compulsive disorder (OCD) has been noted. The response of two patients with OCD and comorbid epilepsy to carbamazepine is reported. It is hypothesized that obsessive compulsive symptoms may be a variant of epileptiform forced thinking in a subgroup of patients, and may be preferentially responsive to anticonvulsant therapy.

Currently, basal ganglia (BG) are considered regulators of motor and emotional activity. It's operationality encompass Obsessive Compulsive Disorder (OCD). The case of a patient suffering with severe OCD is described of note, his symptoms disappeared following a hemorrhage of the left BG. However, once the hemorrhage was reabsorbed his symptoms returned. It is possible that lesions affecting ce...

The purpose of this research was to investigate the specificity of purported relations between symptoms of eating disorders (ED) and obsessive-compulsive disorder (OCD). Whereas most research has focused on diagnostic comorbidity or between-groups analyses, this study took a dimensional approach to investigate specific relations among symptoms of anorexia, bulimia, and OCD, as well as panic, de...

Body dysmorphic disorder (BDD) and obsessive compulsive disorder (OCD) are associated with elevated depression, suicidality, functional impairment, and days housebound, yet little research has identified risk factors for these outcomes. Using path analysis, the present study examined anxiety and shame as risk factors for these outcomes across Internet-recruited self-report groups (BDD [n = 114]...