Purpose To report two rare cases of filamentous fungal keratitis. Methods Two non-consecutive patients presented with suspicious fungal keratitis. After performing the smear and culture, medical therapy was started for them. They underwent slit photography and in vivo confocal microscopy (IVCM) in their follow-up visits. Results The patients were 33-year-old and 56-year-old farmer men. They...

We previously reported on the development and testing of a multi-spectral confocal microendoscope. Here we present a new system that will be used during an early stage clinical trial. The new microendoscope is significantly smaller, uses fewer optical elements, and is structurally more robust. The slit-scanning confocal system employs two synchronized single-axes scan mirrors and an externally ...

We describe a method of optical refocusing for high numerical aperture (NA) systems that is particularly relevant for confocal and multiphoton microscopy. This method avoids the spherical aberration that is common to other optical refocusing systems. We show that aberration-free images can be obtained over an axial scan range of 70 mum for a 1.4 NA objective lens. As refocusing is implemented r...

PURPOSE To investigate corneal thickness, curvature, and morphology with the Orbscan Topography System I (Bausch & Lomb, Inc., Salt Lake City, UT) in patients with Marfan syndrome (MFS) and to study MFS with in vivo confocal microscopy. METHODS This prospective, clinical, comparative case series included 60 eyes of 31 patients with MFS and 32 eyes of 17 control subjects. First, biomicroscopic...

The behavior of confined colloidal suspensions with attractive interparticle interactions is critical to the rational design of materials for directed assembly(1-3), drug delivery(4), improved hydrocarbon recovery(5-7), and flowable electrodes for energy storage(8). Suspensions containing fluorescent colloids and non-adsorbing polymers are appealing model systems, as the ratio of the polymer ra...

Dual-comb microscopy (DCM), an interesting imaging modality based on the optical-frequency-comb (OFC) mode and image pixel one-to-one correspondence, benefits from scan-less full-field simultaneous confocal amplitude phase imaging. However, two fully frequency-stabilized OFC sources requirement hampers DCM practicality due to complexity costs. Here, a bidirectional single-cavity dual-comb fiber...

Abstract Point-wise measuring profilometers like the tactile stylus instruments or optical sensors are established measurement tools in science and industry to measure characterize surface textures. We present a fiber-coupled laser interferometric confocal distance sensor for profiling. The is characterized by small geometric dimensions its high lateral scanning speed. ability specularly reflec...

purpose: to compare clinical and confocal scan outcomes after descemet stripping automated endothelial keratoplasty (dsaek) performed for fuchs’ endothelial dystrophy versus pseudophakic bullous keratopathy. methods: in this retrospective comparative study, 47 consecutive eyes of 39 patients with the diagnosis of fuchs’ endothelial dystrophy (n=29, group 1) or pseudophakic bullous keratopathy (...