Background . With the increased use of combination antiretroviral therapy, mortality people living with HIV has decreased significantly, which led to an increase comorbidity and secondary HIV-related pathology in both adults also children adolescents infection. The incidence infection those general population varies significantly. aim To assess frequency range chronic comorbidities perinatal Me...

Tuberculosis (TB) is a global disease with increase in concern with growing morbidity and mortality after drug resistance and co-infection with HIV. Mother to neonatal transmission of disease is well known. Current recommendations regarding management of newborns of mothers with tuberculosis are variable in different countries and have large gaps in the knowledge and practices. We compare and s...

An autopsy case of congenital tuberculosis is described in a 41-day-old female infant who was born to a mother having active pulmonary tuberculosis. The primary complex was seen in the liver and portal lymph nodes, and there was a generalized miliary dissemination including lung, liver, spleen, pancreas, adrenals, thyroid, thymus, kidneys, brain, and bowel. The organism was confirmed to be Myco...

The results of a survey published by McDonald (1961) suggest that children born to women with pulmonary tuberculosis may show an excess of serious congenital malformations. Among a random sample of 3,295 pregnant women who were interviewed at their first antenatal visit and followed up to ascertain the outcome of their pregnancies, 61 gave a history of pulmonary tuberculosis and four of the chi...

Congenital tuberculosis (TB) is a rare disease with a high mortality rate, and is difficult to diagnose. Here we present a case of congenital TB detected by the T-SPOT.TB assay in a male infant after in vitro fertilization. He ultimately survived after anti-TB therapy despite a delayed diagnosis, and underwent radiological follow-up. The delay in diagnosis of congenital TB resulted in a severe ...

This article presents a case of multi drug-resistant congenital tuberculosis (TB) in an infant. His mother was diagnosed with disseminated TB and treatment commenced 26 days postpartum. The infant was diagnosed with TB after 46 days and died at 2 months and 16 days of age. Congenital transmission of TB to the infant was suspected, because direct postpartum transmission was considered unlikely; ...

Osteomyelitis caused by Mycobacterium tuberculosis is a rare entity. This clinical condition even rarer when the bones of extremities like foot are involved. There paucity literature on isolated tubercular involvement foot. Further, congenital hallux valgus an infrequently reported condition. A case first metatarsal left with without pulmonary never in literature. We herein present its type whe...