نتایج جستجو برای: connexin36

تعداد نتایج: 161  

2010
Logan J. Voss Noortje Mutsaerts James W. Sleigh

Despite much research, there remains controversy over the role of gap junctions in seizure processes. Many studies report anticonvulsant effects of gap junction blockade, but contradictory results have also been reported. The aim of this study was to clarify the role of connexin36 (Cx36) gap junctions in neocortical seizures. We used the mouse neocortical slice preparation to investigate the ef...

2016
Fatemeh Etemadi Mohammad Sayyah Hamid Gholami Pourbadie Vahab Babapour

BACKGROUND GABAergic interneurons in the hippocampal CA1 area are mutually communicated by gap junctions (GJs) composed of connexin36 (Cx36). We examined the role of Cx36 in CA1 in manifestation of kindled seizures and hippocampal kindling in rats. METHODS Quinine, as the specific blocker of Cx36, was injected into CA1, and kindled seizures severity was examined 10 min afterward. Moreover, qu...

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