نتایج جستجو برای: convincing mechanisms
تعداد نتایج: 546453 فیلتر نتایج به سال:
The introduction of forensic autosomal DNA profiles was controversial, but the problems were successfully addressed, and DNA profiling has gone on to revolutionise forensic science. Y-chromosome profiles are valuable when there is a mixture of male-source and female-source DNA, and interest centres on the identity of the male source(s) of the DNA. The problem of evaluating evidential weight is ...
A perfect zero-knowledge interactive protocol allows a prover to convince a veri er of the validity of a statement in a way that does not give the veri er any additional information [GMR,GMW]. Such protocols take place by the exchange of messages back and forth between the prover and the verier. An important measure of e ciency for these protocols is the number of rounds in the interaction. In ...
The issue of risk assessment for carcinogens that appear to act via nongenotoxic mechanisms or at the tumor promotion stage, respectively, is discussed in light of current information on biological mechanisms involved in carcinogenesis as well as interindividual variability in human response. Proposals to treat "nongenotoxic" carcinogens and tumor promoters as posing lower risks to humans are d...
Because of their rare detection in atherosclerotic lesions, the involvement of neutrophils in the pathophysiology of atherosclerosis has been largely denied. However, over the past couple of years, studies have provided convincing evidence for the presence of neutrophils in atherosclerotic plaques and further revealed the causal contribution of neutrophils during various stages of atheroscleros...
Metformin is currently the first-line drug treatment for type 2 diabetes. Besides its glucose-lowering effect, there is interest in actions of the drug of potential relevance to cardiovascular diseases and cancer. However, the underlying mechanisms of action remain elusive. Convincing data place energy metabolism at the center of metformin's mechanism of action in diabetes and may also be of im...
Many trials on probiotics are now published that use established methods to demonstrate their clinical efficacy. Convincing progress has been made in the field of inflammatory bowel disease and allergy prevention in infants. Experimental studies show clear differences (and even sometimes opposite effects) between apparently closely related probiotics and suggest new mechanisms for the observed ...
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