Background: Examining the relationship between cord blood and maternal serum zinc levels and birth weight.Methods: A total of 127 infant-mother pairs were assigned to study (n = 58; with birth weight < 2500 g) and control (n = 69; with birth weight ≥ 2500 g) groups. Serum samples were collected from eligible mothers and cord blood of their low birth weight (LBW) or normal birth weight (NBW) hea...

introduction: umbilical cord blood (cb) has been identified as a rich source for hematopoietic stem cells (hscs), and has provided an alternative to bone marrow transplantation. the use of ex vivo expanded cells has been suggested as a possible means to accelerate the speed of engraftment in cord blood (cb) transplantation. the main aim of our study is to find the best culture media and conditi...

BACKGROUND Polybrominated diphenyl ethers (PBDEs) reduce blood concentrations of thyroid hormones in laboratory animals, but it is unclear whether PBDEs disrupt thyroid hormones in pregnant women or newborn infants. OBJECTIVES We investigated the relationship between maternal PBDE levels and thyroid hormone concentrations in maternal and cord sera. METHODS We used data from the Health Outco...

AIM Exposing a fetus to hyperglycemia can increase the risk for later-life metabolic disorders. Betatrophin has been proposed as a key regulator of pancreatic beta cell proliferation and lipid regulation. Highly responsive to nutritional signals, serum betatrophin concentrations have been found to be altered by various physiological and pathological conditions. We hypothesized that betatrophin ...

BACKGROUND & OBJECTIVES The genesis of atherosclerotic lesions, a major cardiovascular risk factor starts in the early stage of life. If the premature development of cardiovascular risk factors can be anticipated during childhood, cardiovascular events can be prevented effectively by taking appropriate measures. This study was carried out to assess the role of in utero malnutrition in cardiovas...

BACKGROUND Haptocorrin (HC) carries cobalamin analogues (CorA), but whether CorA are produced in the body is unknown. All cobalamins (Cbl) to the foetus are delivered by the Cbl-specific protein transcobalamin (TC), and therefore analysis of cord serum for CorA may help to clarify the origin of CorA. METHODS HC-CorA were quantified in paired samples of cord serum from newborns and serum from ...

AIM There are currently limited lipidomics data for human umbilical cord blood. Therefore, the lipidomes of cord sera from six newborns and sera from six nonpregnant females were compared. MATERIALS & METHODS Sera lipidomics analyses were conducted using a high-resolution mass spectrometry analytical platform. RESULTS Cord serum contained a diverse array of glycerophospholipids, albeit gene...

Abstract Objectives: Controversial findings exist regarding the association between neonate gender and umbilical cord blood lipid levels. This study aims to compare the levels of lipids and lipoprotein B-100 in the umbilical cord blood of male and female newborns and assess the impact of these factors on neonatal anthropometric measurements. Methods: This cross-sectional study was performed on ...