The Capsule Sensitizes Streptococcus pneumoniae to -Defensins Human Neutrophil Proteins 1 to 3 Katharina Beiter,† Florian Wartha,† Robert Hurwitz, Staffan Normark, Arturo Zychlinsky, and Birgitta Henriques-Normark* Department of Bacteriology, Swedish Institute for Infectious Disease Control, 171 82 Solna, Sweden; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, 171 77 ...

Low-flow postural tachycardia syndrome (POTS) is associated with increased plasma angiotensin II (ANG II) and reduced neuronal nitric oxide (NO), which decreases NO-dependent vasodilation. We tested whether the ANG II type 1 receptor (AT(1)R) antagonist losartan would improve NO-dependent vasodilation in POTS patients. Furthermore, if the action of ANG II is dependent on NO, then the NO synthas...

Background and Aim: There have been attempts to restore destroyed primary anterior teeth using a variety of post and core systems, which were able to solve just part of the problems related to this issue. Therefore, the present study aimed to inves-tigate the fracture resistance of restorations supported with a variety of posts and cores in primary anterior teeth. Materials and Methods: The pr...

Functional neuroimaging studies have identified several "core" brain regions that are preferentially activated by scene stimuli, namely posterior parahippocampal gyrus (PHG), retrosplenial cortex (RSC), and transverse occipital sulcus (TOS). The hippocampus (HC), too, is thought to play a key role in scene processing, although no study has yet investigated scene-sensitivity in the HC relative t...

We investigate the problem of approximating the Pareto set of biobjective optimization problems with a given number of solutions. This task is relevant for two reasons: (i) Pareto sets are often computationally hard so approximation is a necessary tradeoff to allow polynomial time algorithms; (ii) limiting explicitly the size of the approximation allows the decision maker to control the expecte...

although there is enough knowledge indicating on the influence of frequency content of input motion on the deformation demand of structures, state-of-the-practice seismic studies use the intensity measures such as peak ground acceleration (pga) which are not frequency dependent. the v max/a max ratio of strong ground motions can be used in seismic hazard studies as the representative of frequen...

We investigate the problem of approximating the Pareto set of biobjective optimization problems with a given number of solutions. This task is relevant for two reasons: (i) Pareto sets are often computationally hard so approximation is a necessary tradeoff to allow polynomial time algorithms; (ii) limiting explicitly the size of the approximation allows the decision maker to control the expecte...