background: anemia is the most common blood disorder observed in vulnerable groups and affects their efficiency in their everyday activities. possible complications of the disease may be reduced or prevented by screening of patients. screening programs impose certain costs upon the health system, which may offset their positive effects. whether the positive impacts of screening outweigh its cos...

breast cancer is the leading cause of malignancy among women. screening using mammography is proposed as an effective intervention for reducing early deaths due to breast cancer. we conducted a systematic review to assess the cost-effectiveness of such screening programs. we searched medline, scopus and google scholar and complemented it by other searches using sensitive search terms from 1993-...

Finding better mechanisms to enable differential pricing that reflects different degrees of willingness to pay across countries with different income levels is an important challenge for drug manufacturers and policy makers. Drug prices must be high enough to meet manufacturers' needs--covering costs and ensuring adequate investment in research and development, as well as producing a profit--bu...

BACKGROUND Psychological therapy groups for people with dementia are widely used, but their cost-effectiveness has not been explored. AIMS To investigate the cost-effectiveness of an evidence-based cognitive stimulation therapy (CST) programme for people with dementia as part of a randomised controlled trial. METHOD A total of 91 people with dementia, living in care homes or the community, ...

Medical technology assessment, which traditionally has involved evaluating whether a technology was safe and effective, has been expanded in recent years to include consideration of cost-effectiveness. While most analysts and policymakers would agree that cost-effectiveness is, in principle, a worthy goal, actually using such a standard in coverage decisions is much more difficult. This Comment...

On the basis of clinical trial data, 13 strategies for initial screening (filtering) for colorectal cancer are modeled for the purpose of economic evaluation. A wide range of detection cost estimates are generated, although ranking options by detection cost ignores the important consideration of undetected cancers. Formulating the problem as one of cost-effectiveness, however, allows the author...

OBJECTIVE To assess the association between different types of organisation and the results from economic evaluations. DESIGN Retrospective pairwise comparison of evidence submitted to the technology appraisal programme of the National Institute for Clinical Excellence (NICE) by manufacturers of the relevant healthcare technologies and by contracted university based assessment groups. DATA ...

Aim of this paper is to propose a framework for the evaluation of tunnel safety. Two methods for the analysis of tunnel safety, the probabilistic and the deterministic approach, and their characteristics have been described. Probabilistic criteria are proposed for the judgment of personal, societal and economic risks of tunnels. Furthermore some methods to analyse cost effectiveness of (additio...

Economic evaluation in the form of cost-effectiveness analysis has become a popular means to inform decisions in healthcare. With multi-regional clinical trials in a global development program becoming a new venue for drug efficacy testing in recent decades, questions in methods for cost-effectiveness analysis in the multi-regional clinical trials setting also emerge. This paper addresses some ...