نتایج جستجو برای: coxibs
تعداد نتایج: 240 فیلتر نتایج به سال:
BACKGROUND In view of the ongoing controversy about potential differences in cardiovascular safety of selective cyclooxygenase (COX)-2 inhibitors (coxibs), we compared the effects of 2 different coxibs and a traditional NSAID on endothelial dysfunction, a well-established surrogate of cardiovascular disease, in salt-induced hypertension. METHODS AND RESULTS Salt-sensitive (DS) and salt-resist...
BACKGROUND Communicating risk is difficult. Although different methods have been proposed - using numbers, words, pictures or combinations - none has been extensively tested. We used electronic and bibliographic searches to review evidence concerning risk perception and presentation. People tend to underestimate common risk and overestimate rare risk; they respond to risks primarily on the basi...
BACKGROUND Although clinical trial results suggest that meloxicam has less gastrointestinal toxicity than most other non-steroidal anti-inflammatory drugs (NSAIDs), in practice it has been associated with a large number of yellow card reports of gastrointestinal complications. AIMS To estimate whether meloxicam and the coxibs, rofecoxib and celecoxib, have been channelled towards high risk pa...
BACKGROUND AND PURPOSE There is limited information regarding the cerebrovascular safety of cyclooxygenase 2 inhibitors (coxibs) and noncoxib nonsteroidal antiinflammatory drugs (NSAIDs). We determined whether specific NSAIDs, including coxibs, are associated with risk of stroke. METHODS Retrospective cohort study among Tennessee Medicaid enrollees aged 50 to 84 years between January 1, 1999 ...
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