The application of finite mixture regression models has recently gained an interest from highway safety researchers because of its considerable potential for addressing unobserved heterogeneity. Finite mixture models assume that the observations of a sample arise from two or more unobserved components with unknown proportions. Both fixed and varying weight parameter models have been shown to be...

Recombination events are not uniformly distributed and often cluster in narrow regions known as recombination hotspots. Several studies using different approaches have dramatically advanced our understanding of recombination hotspot regulation. Population genetic data have been used to map and quantify hotspots in the human genome. Genetic variation in recombination rates and hotspots usage hav...

There is growing evidence that in a variety of organisms the majority of meiotic recombination events occur at a relatively small fraction of loci, known as recombination hotspots. If hotspot activity results from the DNA sequence at or near the hotspot itself (in cis), these hotspots are expected to be rapidly lost due to biased gene conversion, unless there is strong selection in favor of the...

Understanding recombination rate variation is very important for studying genome diversity and evolution, and for investigation of phenotypic association and genetic diseases. Recombination hotspots have been observed in many species and are well studied in yeast. Recent study demonstrated that recombination hotspots are also a ubiquitous feature of the human genome. But the nature of human hot...

Most states currently use ranking procedures to identify intersections with safety concerns. One objective of a state intersection ranking procedure is to provide a reliable start to the prioritization of safety improvements. For efficiency purposes, it is crucial to have a ranking system that identifies intersections with the most severe safety concerns. Otherwise, potentially hazardous inters...

Although speed is considered to be one of the main crash contributory factors, research findings are inconsistent. Independent of the robustness of their statistical approaches, crash frequency models typically employ crash data that are aggregated using spatial criteria (e.g., crash counts by link termed as a link-based approach). In this approach, the variability in crashes between links is e...

xanthomonas campestris pv.musacrearum causes banana wilt disease (bxw disease) which occurs at different epidemic phases in east and central africa (eca). in the endemic areas, there are many banana fields with over 80% bxw disease incidence. this study aimed at rehabilitating banana fields heavily infected with bxw disease in uganda, kenya and dr. congo. farmer managed trials were established ...

Identifying hotspots of species threat has been a successful approach for setting conservation priorities. One important challenge in conservation is that, in many hotspots, export industries continue to drive overexploitation. Conservation measures must consider not just the point f impact, but also the consumer demand that ultimately drives resource use. To understand which species threat hot...