Clinical and histological features provide evidence that immunological reactions of the cell-mediated type are abnormal in some forms of chronic liver disease. By using the leucocyte migration test of Søborg and Bendixen (1967), a correlate of cellular hypersensitivity in vitro, the authors studied the production of the migration inhibitory factor by lymphocytes exposed to a fetal liver homogen...

BACKGROUND/AIMS The aim of this study was to describe the types and causes of liver disease in patients from a single community hospital in Korea between April 2005 and May 2010. METHODS A cohort of patients who visited the liver clinic of the hospital during the aforementioned time period were consecutively enrolled (n=6,307). Consistent diagnostic criteria for each liver disease were set by...

however, history of liver transplantation has started in 1963, but after discovery of anti-rejection drugs such as cyclosporine in 1980s, this method has experienced. from 1984 more than 3000 patients underwent surgery and just 1680 patients in 66 liver transplantation centers have operated in 1988. every patient suffers from severe liver diseases and is in terminal stage of this disease, must ...

Hepatic hemangiomas are considered to be the most common benign tumors of the liver. They are often found incidentally while investigating for other causes of liver disease. Hemangiomas that are less than 10 cm are not expected to cause any problems. Typically, they do not enlarge and, apart from regular follow-up, no definitive treatment is indicated. This is a posthumous case report of a male...

context celiac disease (cd) is defined as a permanent intolerance to ingested gluten. the intolerance to gluten results in immune-mediated damage of small intestine mucosa manifested by villous atrophy and crypt hyperplasia. these abnormalities resolve with initiationa gluten-free diet. evidence acquisition pubmed, ovid, and google were searched for full text articles published between 1963 and...

The objective of this study was to evaluate the frequency of liver disease and its aetiology in a cohort of immigrants. We retrospectively examined the hospital discharge charts of all the immigrant patients presenting at our day hospital from July 2009 to June 2013, and after evaluating the anamnestic, clinical and laboratory data on these charts we identified subjects with liver disease and i...

Nonalcoholic fatty liver disease (NAFLD) is the hepatic manifestation of metabolic syndrome. The increased prevalence of obesity, diabetes, hypertension, hypertriglyceridaemia and hypercholesterolemia are considered to be the potential causative factors for NAFLD. NAFLD is emerging as a major clinical problem worldwide. Recently much attention has been focused in India as the prevalence of obes...

Fatty liver has become the most common liver disorder and is recognized as a major health burden in the Western world. The causes for disease progression are not fully elucidated but lysosomal impairment is suggested. Here we evaluate a possible role for lysosomal acid lipase (LAL) activity in liver disease. To study LAL levels in patients with microvesicular, idiopathic cirrhosis and nonalcoho...

conclusions elevation of liver enzymes appears in 29 % obese children in a tertiary care centre. absolute alanine aminotransferase levels are significantly higher in obese than in overweight children. even obese children with normal liver enzymes show signs of fatty liver disease as demonstrated by liver enzymes at the upper limit of normal. results elevated alanine aminotransferase was observe...

results of 45 patients, 4 (8.9% [95% ci: 4.4-15.6]) had detectable genomic hcv-rna in their pbmc specimens. hcv genotypes were determined in the pbmcs of these subjects showed that 2 (50.0%) subjects with occult hcv infection had hcv subtype 3a, and 2 (50.0%) had hcv subtype 1b. conclusions this study found that 8.9 % of the iranian candidates for liver transplant with cryptogenic cirrhosis had...