A novel compound MS-444 was isolated from the culture broth of a bacterial strain KY7123. The strain was identified as Micromonospora sp. from its morphological and cultural characteristics. The compound inhibited the activity of purified smooth muscle myosin light chain kinase with an IC50 value of 10 microM. The production, isolation, physico-chemical properties and biological activities of M...

Negotiations can be discussed from a broad or a narrow sense: negotiations in a broad sense include all forms of consultation, communication, discussion, exchanging of views, reaching a consensus, and formal negotiations. Those in a narrow sense include the activities that are carried out in places that are publicly or formally prepared for negotiations. The academic circle of negotiations has ...

Ten years ago the Association of Albanian Physicians in Macedonia undertook the very brave step of publishing a scientific medical journal, Medicus, as a platform for publishing biomedical research papers. Medical journal MEDICUS is an international peer-review journal of biomedical science. The first issue was published in 2004, starting with publishing two issues per year. From 2013, the jour...

INTRODUCTION Why is recording ethnicity important? The Race Relations Act of 1968 required all public bodies to consider the race equality implications in all policies. Since then, the official collection of ethnic group statistics has been mandated as an essential first step towards identifying and addressing ethnic inequalities. Capturing ethnic group information in routine health records is ...

Campylobacter fetus subsp. jejuni was isolated from the feces of 14.8% of a random sample of the healthy population of rural southern India. The rate of isolation was highest in preschool children. This finding emphasizes the need to identify markers of pathogenicity in strains of C. fetus subsp. jejuni, which so far are identified only by cultural characteristics. The pathogenic role of this o...

Ceratocystis polonica and C. laricicola are two morphologically similar species that occur on conifers and reside in the Ceratocystis coerulescens species complex. They, however, represent two ecologically distinct entities. C. polonica causes blue stain on Norway spruce (Picea abies) and other spruce species (Picea spp.) in Eurasia and is associated with the bark beetles Ips typographus, I. ty...

Increasing localisation represents one of the most spectacular processes of the economies that develop and transform as a result of globalisation processes: while the (relative) importance of national economies is decreasing, the economic role of regions and cities seems to grow. Global competition has intensified also in space, especially with the growing importance of the knowledge-based econ...

The CIPHER project was set up in April 2002 as a thirty month project supported by the European Union. The project aims to give the public new ways of accessing cultural heritage information from around Europe using new technologies. These technologies are intended to help organise knowledge and cultural heritage narratives. The technology helps to present these narratives on the internet and p...

Rural communities face significant challenges regarding the adequate availability of diagnostic-, treatment-, and support-services for individuals with autism spectrum disorder (ASD). Specifically, a variety of factors, including geographic distance between families and service providers, low reliance on health care professionals, and cultural characteristics, contribute to the diminished avail...