Curcuma spp. extracts, particularly the dietary polyphenol curcumin, prevent colon cancer in rodents. In view of the sparse information on the pharmacodynamics and pharmacokinetics of curcumin in humans, a dose-escalation pilot study of a novel standardized Curcuma extract in proprietary capsule form was performed at doses between 440 and 2200 mg/day, containing 36-180 mg of curcumin. Fifteen p...

An aerobic actinomycete strain isolated from an Indian soil sample and designated No. E864-61 was found to produce in submerged fermentation a new antibiotic complex, Bu-2313 (components A and B). Strain E864-61 forms single, pairs or chains of three to eight spores on the aerial mycelium and its aerial mass color is grayish blue-green. The cell wall of strain E864-61 contains meso-diaminopimel...

The macroscopic and microscopic characters, physical constant values, extractive values, ash values and the behaviour of powder drug on treatment with different chemical regents, microchemical and histochemical analyses were conducted to characterize some pharmacognostical parameters of Curcuma amada linn. (Zingiberaceae).

To asses the effect of turmeric (Curcuma longa) supplementation on antioxidants and immunity of broiler chickens, seventy five run day old coloured synthetic broiler chicks were randomly divided into 3 groups (25 chicks per each) of mixed sex. Group I served as control (without any supplementation), whereas birds in groups II and III were supplemented with 0.5% and 1.0% Curcuma longa powder res...

Curcuma Kwangsiensis S. G. Lee et C. F. Liang originates from the rhizome of the Curcuma Genus which is commonly used in traditional Chinese medicine. Pharmacological studies showed that curzerenone [1], curcumol, curdione, β-elemene, germacrone were the active ingredients of volatile oil from rhizoma curcuma. In addition, they had the effect of anti-inflammation, antibiosis [2], antivirus [3],...

Neocurdione, isoprocurcumenol, and a new sesquiterpene, 9-oxo-neoprocurcumenol, were isolated from fresh rhizomes of Curcuma aromatica and Curcuma zedoaria (Zingiberaceae) as attachment inhibitors against the blue mussel, Mytilus edulis galloprovincialis. The structures of these compounds were elucidated on the basis of spectroscopic evidence.

RATIONALE The active compounds or metabolites of herbal plants exert a definite physiological action on the human body and thus are widely used in human therapy for various diseases including cancer. Previous studies by our group have reported the anticarcinogenic properties of the two herbal plants extracts (HPE) of Aristolochia tagala (AT) Cham. and Curcuma caesia (CC) Roxb. in diethylnitrosa...

background: different treatment and protective approaches for radiation-induced oral mucositis have been practiced and have varieties of success. of which, radioprotective agents, synthetic or natural, have been of great interest for researchers. this study aims to evaluate the effect of curcuma longa topical gel as a herbal production on mucositis induced by radiation therapy of head and neck ...

Mitogen activated protein kinase (MAPK) cascades are universal signal transduction modules that play crucial role in plant growth and development as well as biotic and abiotic stress responses. 20 and 17 MAPKs have been characterized in Arabidopsis and rice respectively, which are used for identification of the putative MAPKs in other higher plants. However, no MAPK gene sequences have yet been...