The MONK user package comprises not only the Monte Carlo code itself but also nuclear data libraries, validation data, documentation, geometry model visualisation tools, productivity tools of various kinds and user support services. In identifying the development direction for the package, input is obtained not only from the two collaborating partners but also from others customers of the ANSWE...

PET/CT has emerged as an important tool in oncology to detect, characterize, and follow-up various tumor entities. The integrated technology includes the respective advantageousness of PET and CT in a synergistic manner combining high sensitivity of PET with transmission correction and anatomic referencing by CT. PET/CT has been proven to be fast, robust and meanwhile widely available in oncolo...

Anna L David, Michael Themis, Simon N Waddington, Lisa Gregory, Suzanne MK Buckley, Megha Nivsarkar, Terry Cook, Donald Peebles, Charles H Rodeck, Charles Coutelle Department of Obstetrics and Gynaecology, Royal Free and University College London Medical School, London WC1E 6HX Gene Therapy Research Group, Section of Cell and Molecular Biology, Division of Biomedical Sciences, Imperial College ...

Mathematical modelling is widely recognized as a powerful and convenient theoretical tool for investigating various aspects of biological evolution and explaining the existing genetic complexity of the real world. It is increasingly apparent that understanding the key mechanisms involved in the processes of species biodiversity, natural selection and inheritance, patterns of animal behaviour an...

The brain is one of the major targets of alcohol actions. Most of the excitatory synaptic transmission in the central nervous system is mediated by N-methyl-D-aspartate (NMDA) receptors. However, one of the most devastating effects of alcohol leads to brain shrinkage, loss of nerve cells at specific regions through a mechanism involving excitotoxicity, oxidative stress. Earlier studies have ind...

Background: Catheter ablation is the treatment of choice for most forms of SVT. Traditionally, fluoroscopy has been the primary tool for visualizing catheter position. However, newer, 3-dimensional mapping technologies offer multiple options for minimizing fluoroscopy use. We review our 8 year experience of a zero-fluoroscopy approach using the Ensite system, and discuss our current techniques....