Cutaneous horns are cornified hyperkeratotic lesions on the skin, usually present photo-exposed areas such as face and scalp. Its presence penis is very rare represents most unusual site. The role of chronic irritation, phimosis, surgical trauma, radiotherapy have been implicated in penile horn formation. Penile elongated, keratinous, white or yellowish projections that range from a few millime...

In mammals with an intact neuraxis, most sympathetic nerve activity is generated by brain stem systems. Therefore these systems have attracted much more attention than spinal systems that generate excitatory inputs to sympathetic preganglionic neurons. The purpose of this study was to determine whether, within hours of C1 spinal cord transection, spinal dorsal horn neurons (DHNs) play a role in...

This essay looks at two papers published by Ed Perl and co-workers that identified specifically nociceptive neurons in the periphery and superficial dorsal horn. Bessou P and Perl ER. Response of cutaneous sensory units with unmyelinated fibers to noxious stimuli. J Neurophysiol 32: 1025–1043 1969. Christensen BN and Perl ER. Spinal neurons specifically excited by noxious or thermal stimuli: ma...

Lumbar dorsal root potentials (DRP) were elicited by nucleus locus coeruleus (LC) stimulation in the cat. Inhibition, by LC stimulation, of dorsal horn cells responding to noxious inputs corresponded in time with the DRPs evoked by LC stimulation. Comparing cutaneous stimulation-evoked DRPs with LC stimulation-evoked DRPs and their respective effects on dorsal horn single-unit activity suggeste...

This essay looks at two papers published by Ed Perl and co-workers that identified specifically nociceptive neurons in the periphery and superficial dorsal horn. Bessou P and Perl ER. Response of cutaneous sensory units with unmyelinated fibers to noxious stimuli. J Neurophysiol 32: 1025-1043 1969. Christensen BN and Perl ER. Spinal neurons specifically excited by noxious or thermal stimuli: ma...