Male of 52 year old with chronic alcoholism and ulcerated lesion on the face and disseminated nodular skin lesions, underwent to biopsy of ulcer edges where was observed a concomitant epidermoid malignancy with Leishmania (L.). Besides others, biopsies of nodule in the periumbilical region, lymph node and bone marrow were assayed, and all biopsies had abundant amastigotes. The amplified Polymer...

  Bronchiolo-alveolar carcinoma with subcutaneous chest wall metastasis is a very rare presentation. A case of 36- year-old male with metastatic subcutaneous chest nodule of bronchiolo-alveolar carcinoma, diagnosed by fine needle aspiration cytology, is reported here. Cutaneous metastases are of diagnostic importance because they may be the first manifestation of an undiscovered internal malig...

A 71-year-old woman was referred to our clinic with a 2-month history of pain and exudate from her right first toe. Physical examination revealed subungual nodule that elevated the nail plate produced distal onycholysis. We performed onychectomy removed nodule. histopathological specimen showed hyperkeratosis acanthosis in epidermis, papillomatosis dilated vessels superficial dermis, aggregatio...

A 47 year old non-parous woman who had never had abdominal surgery was admitted with a four year history of an intermittently palpable nodule in the umbilical region. Initially, she noticed an increase in lesional size and pressure pain, which resolved within a few days. Six months before admission, blue-black discoloration appeared in the umbilical area; this vanishedwithin a week but reappear...

Merkel cell carcinoma is an uncommon, highly malignant, primary cutaneous neuroendocrine tumour mostly occurring as a solitary nodule on the head or on the extremities. It has high recurrence rate. We hereby report a case of Merkel cell carcinoma in a young woman.

Primary cutaneous B-cell lymphomas are non-Hodgkin presenting only in the skin and represent 25% of all primary lymphomas. Based on their clinical behavior, they classified into indolent intermediate forms. Treatment forms includes surgery, radiotherapy, and, extensive disease, rituximab. We report a case 57-year-old woman with single nodule left arm treated surgical excision 5-mm security marg...

The first case of cutaneous clear cell perivascular epithelioid cell tumor (PEComa) with negative HMB-45 marker is presented. The tumor was a nodule 3x2 cm in size, located on the right foot in a 60-year-old man. The lesion consisted of large irregularly shaped cells with clear cytoplasm, negative for S-100 protein, HMB-45, Melan-A, pancytokeratin, epithelial membrane antigen and CAM5.2. Multif...