Polyarteritis nodosa has been the subject of comprehensive reviews covering most of its clinical and histological aspects (Smith and Zeek, 1947; Miller and Daley, 1946; Davson, Ball, and Platt, 1948). There are, however, four points which require clarification, and they are discussed in the present paper: (1) the early changes and the question of the so-called "fibrinoid " substance; (2) some h...

Introduction Cutaneous Polyarteritis Nodosa (cPAN) is a rare type of vasculitis affecting small-to-medium-size arteries. It is distinct from systemic PAN in that it lacks significant internal organ involvement. Familial Mediterranean Fever (FMF) is the most common inherited autoinflammatory disease, characterized by recurrent, self–limited attacks of fever and aseptic polyserositis. PAN is cons...

OBJECTIVES To determine the incidence and clinical features of paediatric primary vasculitis in patients from one centre in Eastern China. METHODS Medical records of paediatric patients diagnosed with primary vasculitis between January 1999 and December 2013 were retrospectively reviewed. For Henoch-Schönlein purpura (HSP) and Kawasaki disease (KD), patients included in the analyses had data ...

A necrotizing arteritis in the uterine cervix is described as an incidental finding in surgical material from 10 patients. The histological features are compared with those seen in polyarteritis nodosa. Subintimal hyaline deposition and a relative paucity of neutrophil and eosinophil polymorphs characterized the lesion but the histological appearance was never sufficiently specific to exclude c...

A case of an 18 year old woman is reported who presented with a pyrexia of unknown origin having returned from a trip to India. She initially had constitutional symptoms only, which rapidly progressed to a multisystem disorder. The difficulty in making the diagnosis of polyarteritis nodosa, especially with the possible differential diagnosis of infection after her recent travel, is discussed. T...

Two young men, were hospitalized due to acute massive blood loss with left abdominal flank pain. In both cases renal angiography showed signs of a haemorrhagic event in the left kidney, perirenal in one and subcapsular in the other. Microaneurysms indicated a diagnosis of polyarteritis nodosa, supported by renal biopsy in one case. Renal haemorrhage is an infrequent presentation of polyarteriti...

Hemobilia, in patients with the diagnosis of polyarteritis nodosa, is rare at clinical presentation and has a grave prognosis. We describe a case of massive hemobilia, due to aneurysmal rupture, in a patient with polyarteritis nodosa. A 39-year-old man was admitted to the hospital with upper abdominal pain. The patient had a history of partial small bowel resection, for intestinal infarction, a...