To cite: Mettu S, Animireddy D, Kanumuri PK, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2016216499 DESCRIPTION Cyclic vomiting syndrome (CVS) is a functional disorder characterised by recurrent, self-limited episodes of intractable nausea and vomiting that are not caused by any specific disease. The episodes occur at variable intervals with prodromal p...

AIMS The medium term prognosis of cyclical vomiting syndrome (CVS) was studied to determine the proportion of affected individuals who had gone on to develop headaches fulfilling the International Headache Society criteria for migraine. METHODS Twenty six (76%) of 34 CVS sufferers identified from the authors' clinical records were traced, and all agreed to participate. Each child was matched ...

Background/Aims The aim of this study was to compare the efficacy and tolerability of topiramate and propranolol in preventing pediatric cyclic vomiting syndrome. Methods A retrospective medical-record review of patients who underwent prophylaxis after receiving a diagnosis of cyclic vomiting syndrome was performed. Patients who completed at least 12 months of treatment were included in the a...